Die folgenden Gennamen und Gensymbole werden für Antigen Cathepsin L über verschiedene Spezies hinweg verwendet:

cathepsin L1 (CTSL1), cathepsin L (Ctsl), cathepsin L1 (Ctsl1), cathepsin L2 (CTSL2), cathepsin L (TcasGA2_TC009486), cathepsin L (CTSL), Cathepsin L (catl), cathepsin L (LOC100305013), cathepsin L1 (ctsl1), cathepsin L1 (Tsp_11596), Cathepsin L1 (catl1)

Zu den weiteren Synonymen zählen:

MEP, CATL, CTSL, FLJ31037, fs, nkt, Ctsl1, 1190035F06Rik, Ctsl, CATHL, CTSL2, CTSL1, LOC663234, 26-29-p, Cp1, ACYPI006974, catl, mep, ctsl, cpl-1, MGC80629, MGC157400, MGC107932

Auf Proteinebene tauchen folgende Bezeichner für Antigen Cathepsin L auf:

cathepsin L1 – cathepsin L – major excreted protein – Cat L – nackt – furless – p39 cysteine proteinase – MEP – CP-2 – cyclic protein 2 – cathepsin L2 – cathepsin L2 preproprotein – 26-29kD-proteinase – cysteine proteinase-1 – Cathepsin L – Cathepsin L1 – cathepsin L1-like

Cathepsin L erfüllt eine Reihe von Funktionen:

cysteine-type endopeptidase activity – peptidase activity – protein binding – aminopeptidase activity – cysteine-type peptidase activity – hydrolase activity – kininogen binding – peptide binding – protein complex binding

Cathepsin L spielt in den folgenden Prozessen eine Rolle:

proteolysis – cell communication – epithelial tube branching involved in lung morphogenesis – metabolic process – Sertoli cell differentiation – autophagic cell death – cellular response to starvation – decidualization – male gonad development – multicellular organismal aging – nerve development – response to glucocorticoid stimulus – response to glucose stimulus – response to gonadotropin stimulus – response to organic cyclic substance – response to protein stimulus – spermatogenesis

Cathepsin L ist wie folgt lokalisiert:

extracellular region – lysosome – apical part of cell – cytoplasm – external side of plasma membrane – microvillus – neuron projection – perikaryon – soluble fraction – stored secretory granule – vacuole

Quelle: NCBI Entrez Gene, Gene Ontology