Die folgenden Gennamen und Gensymbole werden für Antigen Cathepsin B über verschiedene Spezies hinweg verwendet:

cathepsin B (CTSB), cathepsin B (Ctsb), cathepsin B (ctsb), cathepsin B (LOC692390), cathepsin B (Catb-2744), cathepsin B-1674 (Catb-1674), cathepsin B-84 (Catb-84), cathepsin B-3098 (Catb-3098), cathepsin B-16D2 (Catb-16d2), cathepsin B-1874 (Catb-1874), cathepsin B-3483 (Catb-3483), cathepsin B-10270 (Catb-10270)

Zu den weiteren Synonymen zählen:

APPS, CPSB, apps, cpsb, MGC53360, LOC692390, Catb-2744, ACYPI000009, catb-1674a, Catb-84, ACYPI000014, Catb-3098, ACYPI000017, Catb-16d2, catb-16D, ACYPI000018, Catb-1874, ACYPI000019, Catb-3483, ACYPI000020, Catb-10270, ACYPI000021, CTSB, DKFZp459D187

Auf Proteinebene tauchen folgende Bezeichner für Antigen Cathepsin B auf:

cathepsin B – cathepsin B1 – APP secretase – cysteine protease – preprocathepsin B – amyloid precursor protein secretase – RSG-2 – BCSB – cathepsin B-2744 – cathepsin B-1674 – cathepsin B-84 – cathepsin B-3098 – cathepsin B-16D2 – cathepsin B-1874 – cathepsin B-3483 – cathepsin B-10270

Cathepsin B erfüllt eine Reihe von Funktionen:

cysteine-type endopeptidase activity – kininogen binding – peptidase activity – peptide binding – cysteine-type peptidase activity – endopeptidase activity – hydrolase activity – protein complex binding – protein binding

Cathepsin B spielt in den folgenden Prozessen eine Rolle:

proteolysis – regulation of apoptosis – regulation of catalytic activity – response to wounding – negative regulation of cell death – autophagy – response to amine stimulus – response to ethanol – response to glucose stimulus – response to interleukin-4 – response to mechanical stimulus – response to organic cyclic substance – response to peptide hormone stimulus – response to protein stimulus – response to stress – skeletal muscle tissue development

Cathepsin B ist wie folgt lokalisiert:

apical plasma membrane – external side of plasma membrane – extracellular region – intracellular – lysosome – melanosome – mitochondrion – soluble fraction – caveola – cell surface – cytoplasm – extracellular space – perinuclear region of cytoplasm – sarcolemma

Quelle: NCBI Entrez Gene, Gene Ontology