Die folgenden Gennamen und Gensymbole werden für Antigen Caspase 3, Apoptosis-Related Cysteine Peptidase über verschiedene Spezies hinweg verwendet:

caspase 3 (Casp3), death executioner caspase related to Apopain/Yama (decay), Ice (Ice), caspase 3, apoptosis-related cysteine peptidase (CASP3), caspase 3, apoptosis-related cysteine peptidase (casp3), caspase 3 (CASP3)

Zu den weiteren Synonymen zählen:

CC3, Lice, Yama, CPP32, Apopain, Caspase-3, A830040C14Rik, Cas3, Casp3, DECAY, Drosophila executioner caspase related to Apopain/Yama, caspase 3, DmelCG14902, CG14902, DRICE, ICE, DmelCG7788, CG7788, casp3, xcpp32, CASP3

Auf Proteinebene tauchen folgende Bezeichner für Antigen Caspase 3, Apoptosis-Related Cysteine Peptidase auf:

caspase 3 – caspase 3, apoptosis related cysteine protease – death executioner caspase related to Apopain/Yama – CG14902-PA – decay-PA – caspase-3 – decay – caspase-3 protein – cleaved caspase 3 – Ice – CG7788-PA – Ice-PA – caspase 3, apoptosis-related cysteine protease – xcpp32 protein – cysteine protease CPP32

Caspase 3, Apoptosis-Related Cysteine Peptidase erfüllt eine Reihe von Funktionen:

cyclin-dependent protein kinase inhibitor activity – cysteine-type endopeptidase activity – cysteine-type peptidase activity – hydrolase activity – peptidase activity – protein binding

Caspase 3, Apoptosis-Related Cysteine Peptidase spielt in den folgenden Prozessen eine Rolle:

B cell homeostasis – DNA fragmentation involved in apoptosis – T cell homeostasis – apoptosis – cell fate commitment – heart development – induction of apoptosis – induction of apoptosis by oxidative stress – induction of apoptosis via death domain receptors – keratinocyte differentiation – negative regulation of B cell proliferation – negative regulation of activated T cell proliferation – negative regulation of apoptosis – negative regulation of cell cycle – negative regulation of cyclin-dependent protein kinase activity – neuron apoptosis – proteolysis – release of cytochrome c from mitochondria – response to DNA damage stimulus – response to UV – response to wounding – sensory perception of sound – programmed cell death – regulation of retinal cell programmed cell death – response to X-ray – spermatid differentiation

Caspase 3, Apoptosis-Related Cysteine Peptidase ist wie folgt lokalisiert:

cytoplasm – caspase complex

Quelle: NCBI Entrez Gene, Gene Ontology