Die folgenden Gennamen und Gensymbole werden für Antigen Carboxypeptidase E über verschiedene Spezies hinweg verwendet:

carboxypeptidase E (CPE), carboxypeptidase E (Cpe), silver (svr), zgc:85981 (zgc:85981), carboxypeptidase E (cpe), angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 (ACE)

Zu den weiteren Synonymen zählen:

CPH, fat, Cph1, Cph-1, R74677, MGC7101, Cph, CARBE, MGC93638, CG18503, CG32818, CP, CPD, CpepE, EG:171D11.3, EP(X)0356, cc, dwp, l(1)1Bd, poi, slv, DmelCG4122, CG4122, CPE, DCP, ACE1, DCP1, CD143, MVCD3, MGC26566

Auf Proteinebene tauchen folgende Bezeichner für Antigen Carboxypeptidase E auf:

carboxypeptidase E – carboxypeptidase H – silver, isoform D – CG4122-PD – svr-PD – carboxypeptidase – pointed – chlorotic – carboxypeptidase D – dwarp – silver, isoform H – CG4122-PH – svr-PH – silver, isoform E – CG4122-PE – svr-PE – silver, isoform B – CG4122-PB – svr-PB – silver, isoform G – CG4122-PG – svr-PG – silver, isoform F – CG4122-PF – svr-PF – silver, isoform C – CG4122-PC – svr-PC – silver, isoform I – CG4122-PI – svr-PI – carboxypeptidase E-like – angiotensin I converting enzyme 1 – kininase II – peptidase P – CD143 antigen – testicular ECA – carboxycathepsin – dipeptidyl carboxypeptidase 1 – angiotensin converting enzyme, somatic isoform

Carboxypeptidase E erfüllt eine Reihe von Funktionen:

metal ion binding – metallocarboxypeptidase activity – metallopeptidase activity – peptidase activity – zinc ion binding – carboxypeptidase activity – hydrolase activity – cobalt ion binding – protein binding – bradykinin receptor binding – chloride ion binding – drug binding – peptidyl-dipeptidase activity

Carboxypeptidase E spielt in den folgenden Prozessen eine Rolle:

insulin processing – metabolic process – neuropeptide signaling pathway – protein modification process – proteolysis – peptide hormone processing – peptide metabolic process – protein maturation by peptide bond cleavage – chitin-based cuticle development – imaginal disc-derived wing morphogenesis – phagocytosis, engulfment – angiotensin catabolic process in blood – arachidonic acid secretion – blood vessel remodeling – hemopoietic stem cell differentiation – hormone catabolic process – kidney development – mononuclear cell proliferation – peptide catabolic process – regulation of blood pressure – regulation of renal output by angiotensin – regulation of smooth muscle cell migration – regulation of systemic arterial blood pressure by renin-angiotensin – regulation of vasoconstriction – regulation of vasodilation

Carboxypeptidase E ist wie folgt lokalisiert:

extracellular region – plasma membrane – Golgi apparatus – extracellular space – membrane fraction – secretory granule – soluble fraction – cellular_component – endosome – external side of plasma membrane – integral to membrane

Quelle: NCBI Entrez Gene, Gene Ontology