Die folgenden Gennamen und Gensymbole werden für Antigen Calcineurin A über verschiedene Spezies hinweg verwendet:

calcineurin A (Cna), calcineurin A (NFIA_077970), calcineurin A (ACLA_011200), Calcineurin A (PAS_chr3_0414), CaM-dependent protein phosphatase, catalytic subunit (canA), protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (PPP3CA), protein phosphatase 3, catalytic subunit, alpha isoform (Ppp3ca), protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (PPP3CC)

Zu den weiteren Synonymen zählen:

Cna, CALN, CCN1, CNA1, CALNA, PPP2B, CALNA1, CN, CnA, Caln, Calna, AI841391, AW413465, MGC106804, 2900074D19Rik, PPP3CA, PPP3CC

Auf Proteinebene tauchen folgende Bezeichner für Antigen Calcineurin A auf:

calcineurin A – Calcineurin A – CaM-dependent protein phosphatase, catalytic subunit – protein phosphatase-2B – protein serine/threonine phosphatase – protein phosphatase 3, catalytic subunit, alpha isoform – calcineurin A alpha – serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform – PP2BA alpha – PP2B alpha 1 – OTTMUSP00000017685 – protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) – protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform – protein phosphatase 3, catalytic subunit, gamma

Calcineurin A erfüllt eine Reihe von Funktionen:

calcium ion binding – calmodulin binding – protein binding – protein serine/threonine phosphatase activity – hydrolase activity – iron ion binding – zinc ion binding – metal ion binding – phosphoprotein phosphatase activity

Calcineurin A spielt in den folgenden Prozessen eine Rolle:

protein amino acid dephosphorylation – G1/S transition of mitotic cell cycle – calcium ion transport – dephosphorylation – protein import into nucleus – regulation of excitatory postsynaptic membrane potential – regulation of synaptic transmission – response to stress – skeletal muscle fiber development

Calcineurin A ist wie folgt lokalisiert:

calcineurin complex – cytoplasm – cytosol – nucleus – Z disc – microsome – mitochondrion

Quelle: NCBI Entrez Gene, Gene Ontology