Die folgenden Gennamen und Gensymbole werden für Antigen Cadherin 1 über verschiedene Spezies hinweg verwendet:

si:busm1-180o5.2 (si:busm1-180o5.2), cadherin 1, epithelial (cdh1), cadherin 1 (Cdh1), si:busm1-180o5.1 (si:busm1-180o5.1), cadherin 1, type 1, E-cadherin (epithelial) (CDH1), cadherin 1, type 1, E-cadherin (epithelial) (cdh1), cadherin 17, LI cadherin (liver-intestine) (CDH17), Cadherin-17 (cad17), cadherin 17, LI cadherin (liver-intestine) (cdh17)

Zu den weiteren Synonymen zählen:

cdh1, E-cadherin, si:dz180o5.2, dZ71B9.1, si:dz180o5.1, CDH1, uvo, lcam, E-Cad, XBcad, l-cam, xcdh1, cdhc-A, xb-cad, XTCAD-1, c-cadherin, cadherin-1, uvomorulin, XB-cadherin, UVO, CDHE, ECAD, LCAM, Arc-1, CD324, HPT1, CDH16, HPT-1, FLJ26931, MGC138218, MGC142024, cad17, hpt1, cdh16, hpt-1, LI-cadherin, cadherin-17

Auf Proteinebene tauchen folgende Bezeichner für Antigen Cadherin 1 auf:

hypothetical protein LOC368517 – cadherin 1, epithelial – hab – half baked – cadherin 1 – E-cadherin – hypothetical protein LOC368516 – cadherin 1, type 1, E-cadherin (epithelial) – cadherin-1 – cadherin 1, type 1 – uvomorulin – cell-CAM 120/80 – cadherin 1, E-cadherin (epithelial) – calcium-dependent adhesion protein, epithelial – cadherin 17 – LI cadherin – cadherin-16 – HPT-1 cadherin – liver-intestine cadherin – human peptide transporter 1 – human intestinal peptide-associated transporter HPT-1 – Cadherin-17 – cadherin 17, LI cadherin (liver-intestine) – Li cadherin

Cadherin 1 erfüllt eine Reihe von Funktionen:

calcium ion binding – protein binding – RPTP-like protein binding – beta-catenin binding – protein phosphatase binding – transcription activator activity – cell adhesion molecule binding – proton-dependent oligopeptide secondary active transmembrane transporter activity – transporter activity

Cadherin 1 spielt in den folgenden Prozessen eine Rolle:

homophilic cell adhesion – cell adhesion – cell migration involved in gastrulation – cell-cell adhesion – cell-cell adhesion involved in gastrulation – ectoderm development – gastrulation with mouth forming second – germ cell migration – neural tube formation – neuron migration – neuron projection development – pituitary gland development – positive regulation of transcription factor import into nucleus – protein homooligomerization – protein metabolic process – regulation of branching involved in salivary gland morphogenesis – regulation of caspase activity – response to drug – response to organic substance – response to toxin – salivary gland cavitation – synapse assembly – trophectodermal cell differentiation – calcium-dependent cell-cell adhesion – oligopeptide transport – transport

Cadherin 1 ist wie folgt lokalisiert:

membrane – catenin complex – cell cortex – cell-cell adherens junction – desmosome – integral to membrane – microvillus – plasma membrane – Golgi apparatus – actin cytoskeleton – adherens junction – apical part of cell – basolateral plasma membrane – cell-cell junction – cytoplasm – focal adhesion – lateral plasma membrane – perinuclear region of cytoplasm – cell junction

Quelle: NCBI Entrez Gene, Gene Ontology