Die folgenden Gennamen und Gensymbole werden für Antigen CREB Binding Protein über verschiedene Spezies hinweg verwendet:

CREB binding protein (CREBBP), phosphoprotein associated with glycosphingolipid microdomains 1 (PAG1), Csk binding protein (Cbp), phosphoprotein associated with glycosphingolipid microdomains 1 (Pag1), CREB binding protein (Crebbp), CREB binding protein (crebbp), CREB binding protein a (crebbpa)

Zu den weiteren Synonymen zählen:

CBP, RSTS, KAT3A, PAG, FLJ37858, MGC138364, Cbp, Pag, F730007C19Rik, AW558298, CBP/p300, p300/CBP, RTS, CREBBP, cbp, rsts, kat3a, hmm291030, cbp-b, crebbp, si:dkey-206l1.6, si:dkey-44g23.1, Nejire, NV12033

Auf Proteinebene tauchen folgende Bezeichner für Antigen CREB Binding Protein auf:

CREB binding protein – phosphoprotein associated with glycosphingolipid microdomains 1 – Csk-binding protein – phosphoprotein associated with glycosphingolipid-enriched microdomains – Csk binding protein – phosphoprotein-associated with GEMs – phosphoprotein transmembrane adaptor 1 – CREB-binding protein – CREB binding protein (Rubinstein-Taybi syndrome)

CREB Binding Protein erfüllt eine Reihe von Funktionen:

MyoD binding – acetyltransferase activity – histone acetyltransferase activity – metal ion binding – p53 binding – signal transducer activity – transcription coactivator activity – transcription factor activity – transferase activity – zinc ion binding – SH2 domain binding – SH3/SH2 adaptor activity – protein binding – transmembrane receptor protein tyrosine kinase adaptor protein activity – DNA binding – SMAD binding – chromatin binding – peroxisome proliferator activated receptor binding – sequence-specific DNA binding transcription factor activity – transcription activator activity – transcription cofactor activity – transcription factor binding

CREB Binding Protein spielt in den folgenden Prozessen eine Rolle:

N-terminal peptidyl-lysine acetylation – histone acetylation – homeostatic process – interspecies interaction between organisms – positive regulation of transcription – protein complex assembly – regulation of transcription, DNA-dependent – response to hypoxia – signal transduction – immune response – intracellular signaling cascade – negative regulation of T cell activation – cell proliferation – germ-line stem cell maintenance – positive regulation of transcription factor activity – positive regulation of transcription from RNA polymerase II promoter – positive regulation of transcription, DNA-dependent – regulation of S phase – regulation of transcription – transcription

CREB Binding Protein ist wie folgt lokalisiert:

cytoplasm – histone acetyltransferase complex – nucleus – integral to membrane – membrane raft – plasma membrane – integral to plasma membrane – membrane – PML body – outer kinetochore of condensed chromosome – protein complex – transcription factor complex – nuclear body

Quelle: NCBI Entrez Gene, Gene Ontology