Die folgenden Gennamen und Gensymbole werden für Antigen CDC14 über verschiedene Spezies hinweg verwendet:

cdc14, isoform A (cdc14), tyrosine-protein phosphatase CDC14 (cdc14), Cdc14p (CDC14), SIN component Cdc14 (cdc14), hypothetical protein (CDC14), Protein tyrosine phosphatase CDC14 (CDC14), cell division cycle protein 14 (CDC14), hypothetical protein (cdc14), protein phosphatase required for mitotic exit, putative (CDC14)

Zu den weiteren Synonymen zählen:

CDC-14, CDC14, CG7134, DmelCG7134, OAF3

Auf Proteinebene tauchen folgende Bezeichner für Antigen CDC14 auf:

cdc14, isoform A – CG7134-PA – cdc14-PA – cdc14, isoform C – CG7134-PC – cdc14-PC – cdc14, isoform B – CG7134-PB – cdc14-PB – tyrosine-protein phosphatase CDC14 – Cdc14p – Protein phosphatase required for mitotic exit; located in the nucleolus until liberated by the FEAR and Mitotic Exit Network in anaphase, enabling it to act on key substrates to effect a decrease in CDK/B-cyclin activity and mitotic exit – SIN component Cdc14 – hypothetical protein – Protein tyrosine phosphatase CDC14 – cell division cycle protein 14 – protein phosphatase required for mitotic exit, putative – tyrosine-protein phosphatase CDC14, putative

CDC14 erfüllt eine Reihe von Funktionen:

protein tyrosine phosphatase activity – protein tyrosine/serine/threonine phosphatase activity – hydrolase activity – phosphatase activity – phosphoprotein phosphatase activity – transferase activity, transferring phosphorus-containing groups – protein binding

CDC14 spielt in den folgenden Prozessen eine Rolle:

protein dephosphorylation – cell cycle – dephosphorylation – mitotic cell cycle – nucleolus organization – regulation of cell cycle – regulation of exit from mitosis – barrier septum formation involved in cell cycle cytokinesis – cellular protein localization – regulation of mitotic cell cycle – septation initiation signaling cascade

CDC14 ist wie folgt lokalisiert:

RENT complex – cytoplasm – nucleolus – nucleus – spindle pole body

Quelle: NCBI Entrez Gene, Gene Ontology