Die folgenden Gennamen und Gensymbole werden für Antigen CD97 Molecule über verschiedene Spezies hinweg verwendet:

protein tyrosine phosphatase, receptor type, C (Ptprc)

Zu den weiteren Synonymen zählen:

Lca, RT7, CD45, L-CA, T200

Auf Proteinebene tauchen folgende Bezeichner für Antigen CD97 Molecule auf:

receptor-type tyrosine-protein phosphatase C – T200 glycoprotein – leucocyte common antigen – leukocyte common antigen A – leukocyte common antigen B – Protein tyrosine phosphatase, receptor-type, c polypeptide

CD97 Molecule erfüllt eine Reihe von Funktionen:

heparan sulfate proteoglycan binding – heparin binding – hydrolase activity – protein binding – protein kinase binding – protein kinase regulator activity – protein tyrosine phosphatase activity – transmembrane receptor protein tyrosine phosphatase activity

CD97 Molecule spielt in den folgenden Prozessen eine Rolle:

B cell differentiation – B cell proliferation – B cell receptor signaling pathway – T cell differentiation – T cell proliferation – T cell receptor signaling pathway – activation of MAPK activity – defense response to virus – dephosphorylation – heterotypic cell-cell adhesion – immunoglobulin biosynthetic process – leukocyte cell-cell adhesion – negative regulation of T cell mediated cytotoxicity – negative regulation of cytokine-mediated signaling pathway – negative regulation of peptidyl-tyrosine phosphorylation – negative regulation of protein amino acid autophosphorylation – negative regulation of protein kinase activity – negative thymic T cell selection – positive regulation of B cell proliferation – positive regulation of MAPKKK cascade – positive regulation of T cell differentiation – positive regulation of T cell mediated cytotoxicity – positive regulation of T cell mediated immunity – positive regulation of T cell proliferation – positive regulation of alpha-beta T cell proliferation – positive regulation of antigen receptor-mediated signaling pathway – positive regulation of apoptosis – positive regulation of gamma-delta T cell differentiation – positive regulation of humoral immune response mediated by circulating immunoglobulin – positive regulation of isotype switching to IgG isotypes – positive thymic T cell selection – protein amino acid dephosphorylation – regulation of B cell differentiation – regulation of B cell receptor signaling pathway – regulation of S phase – regulation of apoptosis – regulation of cell cycle – regulation of humoral immune response mediated by circulating immunoglobulin – release of sequestered calcium ion into cytosol – response to gamma radiation

CD97 Molecule ist wie folgt lokalisiert:

cell surface – external side of plasma membrane – focal adhesion – integral to membrane – integral to plasma membrane – internal side of plasma membrane – membrane raft – plasma membrane

Quelle: NCBI Entrez Gene, Gene Ontology