Die folgenden Gennamen und Gensymbole werden für Antigen CCCTC-Binding Factor (Zinc Finger Protein)-Like über verschiedene Spezies hinweg verwendet:

CCCTC-binding factor (zinc finger protein)-like (Ctcfl), CCCTC-binding factor (zinc finger protein)-like (CTCFL), CCCTC-binding factor (zinc finger protein)-like (LOC100360757), CCCTC-binding factor (zinc finger protein) (CTCF), CCCTC-binding factor (Ctcf), CCCTC-binding factor (zinc finger protein) (Ctcf), CCCTC-binding factor (zinc finger protein) (ctcf), CCCTC-binding factor (zinc finger protein)-like (CH242-98D1.4), CCCTC-binding factor (zinc finger protein) (LOC100224119)

Zu den weiteren Synonymen zählen:

CTCFL, Boris, RP23-44L6.1, OTTMUSG00000016680, BORIS, CT27, CTCF-T, MGC163358, dJ579F20.2, AW108038, CTCF, im:7152666, xctcf

Auf Proteinebene tauchen folgende Bezeichner für Antigen CCCTC-Binding Factor (Zinc Finger Protein)-Like auf:

CCCTC-binding factor (zinc finger protein)-like – CCCTC-binding factor-like protein – BORIS – CTCF paralog – CTCF-like protein – OTTMUSP00000018045 – Transcriptional repressor CTCFL – Brother of the regulator of imprinted sites – likely orthologue of H. sapiens CCCTC-binding factor-like protein (CTCFL) – brother of the regulator of imprinted sites – brother of regulator of imprinted sites – transcriptional repressor CTCFL-like – BORIS-like protein – OTTHUMP00000174287 – cancer/testis antigen 27 – CCCTC-binding factor – CTCFL paralog – 11-zinc finger protein – transcriptional repressor CTCF – 11 zinc finger transcriptional repressor – OTTMUSP00000018870 – CCCTC-binding factor (zinc finger protein) – transcriptional repressor CTCF-like

CCCTC-Binding Factor (Zinc Finger Protein)-Like erfüllt eine Reihe von Funktionen:

DNA binding – histone binding – metal ion binding – nucleic acid binding – sequence-specific DNA binding – zinc ion binding – promoter binding – transcription activator activity – chromatin insulator sequence binding – protein binding – transcription corepressor activity – transcription factor activity

CCCTC-Binding Factor (Zinc Finger Protein)-Like spielt in den folgenden Prozessen eine Rolle:

DNA methylation during gametogenesis – chromatin modification – genetic imprinting – histone methylation – regulation of transcription – transcription – cell cycle – positive regulation of gene expression – regulation of histone H3-K4 methylation – DNA methylation – chromosome segregation – maintenance of DNA methylation – negative regulation of transcription, DNA-dependent – nucleosome positioning – positive regulation of transcription, DNA-dependent – regulation of centromeric sister chromatid cohesion – regulation of molecular function, epigenetic – dosage compensation, by inactivation of X chromosome – negative regulation of gene expression – regulation of histone acetylation – regulation of histone methylation – regulation of transcription, DNA-dependent

CCCTC-Binding Factor (Zinc Finger Protein)-Like ist wie folgt lokalisiert:

cytoplasm – intracellular – nucleus – chromosome, centromeric region – condensed chromosome – nucleolus – nucleoplasm

Quelle: NCBI Entrez Gene, Gene Ontology