Die folgenden Gennamen und Gensymbole werden für Antigen CCCTC-Binding Factor (Zinc Finger Protein) über verschiedene Spezies hinweg verwendet:

CCCTC-binding factor (zinc finger protein) (CTCF), CCCTC-binding factor (Ctcf), CCCTC-binding factor (zinc finger protein) (Ctcf), CCCTC-binding factor (zinc finger protein) (ctcf), CCCTC-binding factor (zinc finger protein) (LOC100224119), insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2)

Zu den weiteren Synonymen zählen:

AW108038, CTCF, im:7152666, xctcf, p62, IMP2, IMP-2, VICKZ2

Auf Proteinebene tauchen folgende Bezeichner für Antigen CCCTC-Binding Factor (Zinc Finger Protein) auf:

CCCTC-binding factor – CTCFL paralog – 11-zinc finger protein – transcriptional repressor CTCF – 11 zinc finger transcriptional repressor – OTTMUSP00000018870 – CCCTC-binding factor (zinc finger protein) – transcriptional repressor CTCF-like – insulin-like growth factor 2 mRNA binding protein 2 – IGF-II mRNA-binding protein 2

CCCTC-Binding Factor (Zinc Finger Protein) erfüllt eine Reihe von Funktionen:

chromatin insulator sequence binding – metal ion binding – promoter binding – protein binding – transcription activator activity – transcription corepressor activity – transcription factor activity – zinc ion binding – DNA binding – nucleic acid binding – RNA binding – mRNA 5'-UTR binding – nucleotide binding – translation regulator activity

CCCTC-Binding Factor (Zinc Finger Protein) spielt in den folgenden Prozessen eine Rolle:

DNA methylation – chromatin modification – chromosome segregation – genetic imprinting – maintenance of DNA methylation – negative regulation of transcription, DNA-dependent – nucleosome positioning – positive regulation of gene expression – positive regulation of transcription, DNA-dependent – regulation of centromeric sister chromatid cohesion – regulation of molecular function, epigenetic – dosage compensation, by inactivation of X chromosome – negative regulation of gene expression – regulation of histone acetylation – regulation of histone methylation – regulation of transcription – regulation of transcription, DNA-dependent – transcription – anatomical structure morphogenesis – biological_process – negative regulation of translation – regulation of cytokine biosynthetic process

CCCTC-Binding Factor (Zinc Finger Protein) ist wie folgt lokalisiert:

chromosome, centromeric region – condensed chromosome – intracellular – nucleolus – nucleoplasm – nucleus – cytoplasm – cytoskeletal part

Quelle: NCBI Entrez Gene, Gene Ontology