Die folgenden Gennamen und Gensymbole werden für Antigen Breast Cancer 2, Early Onset über verschiedene Spezies hinweg verwendet:

breast cancer 2, early onset (BRCA2), Breast cancer 2, early onset homolog (Brca2), breast cancer 2 (Brca2), breast cancer 2, early onset (brca2)

Zu den weiteren Synonymen zählen:

FAD, FACD, FAD1, BRCC2, FANCB, FANCD, FANCD1, BROVCA2, 30169, BcDNA:SD25109, brca2, CG13583, CG13584, CG30169, DmelCG30169, Brca2, BRCA2

Auf Proteinebene tauchen folgende Bezeichner für Antigen Breast Cancer 2, Early Onset auf:

breast cancer 2, early onset – breast cancer 2 tumor suppressor – BRCA1/BRCA2-containing complex, subunit 2 – breast cancer susceptibility protein BRCA2 – breast and ovarian cancer susceptibility gene, early onset – breast cancer 2, early onset homolog – CG30169-PA – Brca2-PA – breast cancer 2 – breast cancer susceptibility protein 2 – breast cancer 2, mutation 1, University of Wisconsin-Madison – fancd1 – breast and ovarian cancer susceptibility protein 2 – breast cancer type 2 susceptibility protein-like

Breast Cancer 2, Early Onset erfüllt eine Reihe von Funktionen:

gamma-tubulin binding – histone acetyltransferase activity – protein binding – single-stranded DNA binding – transcription activator activity

Breast Cancer 2, Early Onset spielt in den folgenden Prozessen eine Rolle:

DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis – DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator – DNA recombination – brain development – cell aging – centrosome duplication – chordate embryonic development – chromosome organization – cytokinesis during cell cycle – double-strand break repair via homologous recombination – female gonad development – inner cell mass cell proliferation – male meiosis I – mammary gland development – multicellular organism growth – negative regulation of mammary gland epithelial cell proliferation – nucleotide-excision repair – oocyte maturation – positive regulation of mitotic cell cycle – regulation of S phase of mitotic cell cycle – regulation of transcription, DNA-dependent – replication fork protection – response to DNA damage stimulus – response to UV-C – response to X-ray – response to estrogen stimulus – response to gamma radiation – response to genistein – response to nutrient – spermatogenesis – cellular response to DNA damage stimulus – meiotic recombination checkpoint – DNA damage response, signal transduction resulting in induction of apoptosis – cell proliferation – double-strand break repair – hemocyte proliferation – hemopoiesis – DNA repair

Breast Cancer 2, Early Onset ist wie folgt lokalisiert:

BRCA2-MAGE-D1 complex – centrosome – cytoplasm – nucleoplasm – nucleus – secretory granule – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology