Die folgenden Gennamen und Gensymbole werden für Antigen Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide über verschiedene Spezies hinweg verwendet:

branched chain keto acid dehydrogenase E1, alpha polypeptide (BCKDHA), branched chain ketoacid dehydrogenase E1, alpha polypeptide (Bckdha), branched chain keto acid dehydrogenase E1, alpha polypeptide (bckdha), branched chain keto acid dehydrogenase E1, alpha polypeptide (LOC100352048), 2-oxoisovalerate dehydrogenase alpha subunit (branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha) (BCKDE1A) (BckdhA)

Zu den weiteren Synonymen zählen:

MSU, MSUD1, OVD1A, BCKDE1A, FLJ45695, E1a, BCKDA, BCKDHA, wu:fd20d04, zgc:110049

Auf Proteinebene tauchen folgende Bezeichner für Antigen Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide auf:

branched chain keto acid dehydrogenase E1, alpha polypeptide – 2-oxoisovalerate dehydrogenase (lipoamide) – 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial – BCKAD E1[a] – BCKDH E1-alpha – branched chain alpha-ketoacid dehydrogenase subunit E1 alpha – branched chain keto acid dehydrogenase subunit E1, alpha polypeptide – branched-chain alpha-keto acid dehydrogenase E1 component alpha chain – branched chain keto acid dehydrogenase E1, alpha polypeptide (maple syrup urine disease) – BCKDE1A – branched chain keto acid dehydrogenase E1 alpha polypeptide – 2-oxoisovalerate dehydrogenase alpha subunit (branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha) (BCKDE1A)

Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide erfüllt eine Reihe von Funktionen:

3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity – alpha-ketoacid dehydrogenase activity – carboxy-lyase activity – cyclin-dependent protein kinase 5 activator regulator activity – metal ion binding – potassium ion binding – protein complex binding – oxidoreductase activity – oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor – 2-oxoisovalerate dehydrogenase (acylating) activity – molecular_function – protein binding

Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide spielt in den folgenden Prozessen eine Rolle:

branched chain family amino acid catabolic process – oxidation reduction – positive regulation of transcription, DNA-dependent – response to cAMP – response to glucocorticoid stimulus – response to nutrient – metabolic process

Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide ist wie folgt lokalisiert:

mitochondrial alpha-ketoglutarate dehydrogenase complex – mitochondrial matrix – mitochondrion – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology