Die folgenden Gennamen und Gensymbole werden für Antigen Bone Morphogenetic Protein 2 über verschiedene Spezies hinweg verwendet:

bone morphogenetic protein 2 (BMP2), bone morphogenetic protein 2 (Bmp2), bone morphogenetic protein 2 B (bmp2-b), bone morphogenetic protein 2 (bmp2), bone morphogenetic protein 2 (BMP-2), Bone morphogenetic protein 2 (bmp2)

Zu den weiteren Synonymen zählen:

BMP2A, Bmp2a, AI467020, BMP2, bmp2-b, BMP-2, bmp2a, xbmp2, xBMP-2, MGC114605, MGC159940

Auf Proteinebene tauchen folgende Bezeichner für Antigen Bone Morphogenetic Protein 2 auf:

bone morphogenetic protein 2 – OTTMUSP00000016666 – morphogen – Bone morphogenetic protein 2 – bone morphogenetic protein 2-like

Bone Morphogenetic Protein 2 erfüllt eine Reihe von Funktionen:

SMAD binding – cytokine activity – growth factor activity – specific transcriptional repressor activity – protein binding – retinol dehydrogenase activity – protein domain specific binding – protein homodimerization activity – receptor binding

Bone Morphogenetic Protein 2 spielt in den folgenden Prozessen eine Rolle:

BMP signaling pathway – branching involved in ureteric bud morphogenesis – cardiac cell differentiation – cardiac epithelial to mesenchymal transition – cartilage development – cell fate commitment – cell-cell signaling – embryonic development – growth – inflammatory response – negative regulation of cell cycle – negative regulation of cell proliferation – negative regulation of gene-specific transcription – odontogenesis of dentine-containing tooth – organ morphogenesis – positive regulation of astrocyte differentiation – positive regulation of bone mineralization – positive regulation of osteoblast differentiation – positive regulation of pathway-restricted SMAD protein phosphorylation – positive regulation of transcription – positive regulation of transcription from RNA polymerase II promoter – bone mineralization – cell differentiation – epithelial to mesenchymal transition – multicellular organismal development – ossification – osteoblast differentiation – positive regulation of cell differentiation – positive regulation of gene-specific transcription from RNA polymerase II promoter – positive regulation of ossification – positive regulation of protein amino acid phosphorylation – transforming growth factor beta receptor signaling pathway – ovulation cycle – response to mechanical stimulus – response to retinoic acid

Bone Morphogenetic Protein 2 ist wie folgt lokalisiert:

extracellular region – extracellular space – cytoplasm – membrane-bounded vesicle – protein complex

Quelle: NCBI Entrez Gene, Gene Ontology