Die folgenden Gennamen und Gensymbole werden für Antigen Bloom Syndrome, RecQ Helicase-Like über verschiedene Spezies hinweg verwendet:

Bloom syndrome, RecQ helicase-like (BLM), bloom syndrome protein (PITG_10518), Bloom syndrome (blm-A), Bloom syndrome (BLM), Bloom syndrome (blm)

Zu den weiteren Synonymen zählen:

BS, RECQ2, RECQL2, RECQL3, MGC126616, MGC131618, MGC131620, BLM, blm-A, xBLM, ORF1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Bloom Syndrome, RecQ Helicase-Like auf:

Bloom syndrome protein – Bloom syndrome, RecQ helicase-like – bloom syndrome protein – Bloom syndrome – Gd BLM – Bloom's syndrome protein homolog

Bloom Syndrome, RecQ Helicase-Like erfüllt eine Reihe von Funktionen:

ATP binding – ATP-dependent 3'-5' DNA helicase activity – ATPase activity – DNA binding – DNA strand annealing activity – G-quadruplex DNA binding – bubble DNA binding – four-way junction helicase activity – helicase activity – hydrolase activity – hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides – nucleotide binding – p53 binding – ATP-dependent helicase activity – protein binding

Bloom Syndrome, RecQ Helicase-Like spielt in den folgenden Prozessen eine Rolle:

DNA repair – DNA replication – G2 phase of mitotic cell cycle – G2/M transition DNA damage checkpoint – alpha-beta T cell differentiation – cellular metabolic process – chromosome organization – double-strand break repair via homologous recombination – negative regulation of cell division – negative regulation of mitotic recombination – positive regulation of alpha-beta T cell proliferation – positive regulation of transcription – protein oligomerization – regulation of binding – regulation of cyclin-dependent protein kinase activity – replication fork processing – replication fork protection – response to DNA damage stimulus – response to X-ray – telomere maintenance – DNA recombination

Bloom Syndrome, RecQ Helicase-Like ist wie folgt lokalisiert:

PML body – chromosome, telomeric region – cytoplasm – intracellular – lateral element – male germ cell nucleus – nuclear matrix – nucleolus – pronucleus – replication fork – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology