Die folgenden Gennamen und Gensymbole werden für Antigen Basic Fibroblast Growth Factor über verschiedene Spezies hinweg verwendet:

fibroblast growth factor 2 (Fgf2), fibroblast growth factor 2 (basic) (FGF2), basic fibroblast growth factor (BFGF)

Zu den weiteren Synonymen zählen:

Fgfb, bFGF, Fgf-2, FGF2, BFGF, HBGF2

Auf Proteinebene tauchen folgende Bezeichner für Antigen Basic Fibroblast Growth Factor auf:

fibroblast growth factor 2 – basic fibroblast growth factor – fibroblast growth factor 2 (basic) – prostatropin – heparin-binding growth factor 2

Basic Fibroblast Growth Factor erfüllt eine Reihe von Funktionen:

growth factor activity – heparin binding – protein binding – nerve growth factor receptor binding – voltage-gated calcium channel activity

Basic Fibroblast Growth Factor spielt in den folgenden Prozessen eine Rolle:

activation of MAPKK activity – angiogenesis – apoptosis – cell differentiation – glial cell differentiation – induction of an organ – lung development – multicellular organismal development – negative regulation of cell proliferation – positive regulation of angiogenesis – positive regulation of cell differentiation – positive regulation of cell division – positive regulation of cell proliferation – positive regulation of epithelial cell proliferation – positive regulation of granule cell precursor proliferation – positive regulation of protein amino acid phosphorylation – positive regulation of transcription from RNA polymerase II promoter – regulation of retinal cell programmed cell death – C21-steroid hormone biosynthetic process – cell migration involved in sprouting angiogenesis – fibroblast growth factor receptor signaling pathway – negative regulation of blood vessel endothelial cell migration – negative regulation of cell growth – negative regulation of transcription, DNA-dependent – nuclear translocation of MAPK – positive regulation of blood vessel endothelial cell migration – positive regulation of cardiac muscle cell proliferation – positive regulation of transcription – protein kinase cascade – regulation of calcium ion-dependent exocytosis – regulation of transcription, DNA-dependent – signal transduction – synaptic transmission – wound healing

Basic Fibroblast Growth Factor ist wie folgt lokalisiert:

extracellular space – cytoplasm – extracellular region – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology