Die folgenden Gennamen und Gensymbole werden für Antigen BRCA1/BRCA2-Containing Complex, Subunit 3 über verschiedene Spezies hinweg verwendet:

BRCA1/BRCA2-containing complex, subunit 3 (Brcc3), BRCA1/BRCA2-containing complex, subunit 3 (BRCC3), MGC99130 protein (MGC99130), DEP domain containing 1B (depdc1b), BRCA1/BRCA2-containing complex subunit 3 (brcc3), BRCA1/BRCA2-containing complex, subunit 3 (LOC100339276), BRCA1/BRCA2-containing complex, subunit 3 (BRCC36)

Zu den weiteren Synonymen zählen:

CXorf53, MGC99130, brcc3, brcc36, BRCC3, xtp1, BRCC36, DKFZp459H1729

Auf Proteinebene tauchen folgende Bezeichner für Antigen BRCA1/BRCA2-Containing Complex, Subunit 3 auf:

BRCA1/BRCA2-containing complex, subunit 3 – c6.1A – MGC99130 protein – BRISC complex subunit BRCC36 – BRCA1-A complex subunit BRCC36 – Lys-63-specific deubiquitinase BRCC36 – BRCA1/BRCA2-containing complex subunit 3 – BRCA1/BRCA2-containing complex subunit 36 – lys-63-specific deubiquitinase BRCC36 – DEP domain containing 1B

BRCA1/BRCA2-Containing Complex, Subunit 3 erfüllt eine Reihe von Funktionen:

enzyme regulator activity – metal ion binding – metallopeptidase activity – peptidase activity – polyubiquitin binding – protein binding – ubiquitin thiolesterase activity – ubiquitin-specific protease activity – zinc ion binding

BRCA1/BRCA2-Containing Complex, Subunit 3 spielt in den folgenden Prozessen eine Rolle:

G2/M transition DNA damage checkpoint – chromatin modification – double-strand break repair – histone H2A K63-linked deubiquitination – modification-dependent protein catabolic process – positive regulation of DNA repair – response to DNA damage stimulus – response to X-ray – response to ionizing radiation

BRCA1/BRCA2-Containing Complex, Subunit 3 ist wie folgt lokalisiert:

BRCA1-A complex – BRISC complex – nuclear ubiquitin ligase complex – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology