Die folgenden Gennamen und Gensymbole werden für Antigen BRCA1 Associated RING Domain 1 über verschiedene Spezies hinweg verwendet:

BRCA1 associated RING domain 1 (BARD1), BRCA1 associated RING domain 1 (Bard1), novel protein similar to vertebrate BRCA1 associated RING domain 1 (BARD1) (CH211-207D8.3), BRCA1 associated RING domain 1 (LOC100229796), BRCA1 associated RING domain 1 (bard1)

Zu den weiteren Synonymen zählen:

ENSMUSG00000060893, ENSMUSG00000073653, BARD1, LOC100147913

Auf Proteinebene tauchen folgende Bezeichner für Antigen BRCA1 Associated RING Domain 1 auf:

BRCA1 associated RING domain 1 – BRCA1-associated RING domain gene 1 – BRCA1-associated RING domain protein 1 – BRCA1-associated RING domain protein 1-like

BRCA1 Associated RING Domain 1 erfüllt eine Reihe von Funktionen:

RNA binding – kinase binding – ligase activity – metal ion binding – protein binding – protein heterodimerization activity – protein homodimerization activity – ubiquitin-protein ligase activity – zinc ion binding

BRCA1 Associated RING Domain 1 spielt in den folgenden Prozessen eine Rolle:

DNA repair – cell cycle arrest – modification-dependent protein catabolic process – negative regulation of apoptosis – negative regulation of mRNA 3'-end processing – negative regulation of protein export from nucleus – positive regulation of apoptosis – positive regulation of protein catabolic process – protein ubiquitination – regulation of phosphorylation – response to DNA damage stimulus – tissue homeostasis

BRCA1 Associated RING Domain 1 ist wie folgt lokalisiert:

BRCA1-A complex – BRCA1-BARD1 complex – cytoplasm – intracellular – nucleus – ubiquitin ligase complex

Quelle: NCBI Entrez Gene, Gene Ontology