Die folgenden Gennamen und Gensymbole werden für Antigen Breast Cancer 1, Early Onset über verschiedene Spezies hinweg verwendet:

breast cancer 1, early onset (BRCA1), breast cancer 1, early onset (brca1), breast cancer 1, early onset (LOC100224649), breast cancer 1, early onset (LOC100347269), breast and ovarian cancer susceptibility protein (BRCA1), breast cancer 1 (Brca1), protein BREAST CANCER SUSCEPTIBILITY 1-like protein (BRCA1)

Zu den weiteren Synonymen zählen:

BRCA1, iris, pscp, brcai, brcc1, rnf53, brca1, LOC100224649, IRIS, PSCP, BRCAI, BRCC1, RNF53, BROVCA1, ARABIDOPSIS THALIANA BREAST CANCER SUSCEPTIBILITY1, ATBRCA1, breast cancer susceptibility1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Breast Cancer 1, Early Onset auf:

breast cancer 1, early onset – BRCA1 homologue – BRCA1 homolog – breast and ovarian cancer susceptibility protein 1 – Breast cancer type 1 susceptibility protein homolog – BRCA1-like – breast and ovarian cancer susceptibility protein – breast cancer type 1 susceptibility protein homolog – RING finger protein 53 – BRCA1 isoform E1aA-∆2-17 – BRCA1 isoform PI21-∆2-21 – BRCA1/BRCA2-containing complex, subunit 1 – breast and ovarian cancer sususceptibility protein – breast cancer 1 – OTTMUSP00000002773 – breast cancer associated 1 – protein BREAST CANCER SUSCEPTIBILITY 1-like protein

Breast Cancer 1, Early Onset erfüllt eine Reihe von Funktionen:

DNA binding – damaged DNA binding – ligase activity – metal ion binding – protein binding – zinc ion binding – NAD or NADH binding – glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity – ubiquitin-protein ligase activity – androgen receptor binding – enzyme binding – identical protein binding – transcription coactivator activity – tubulin binding – RNA binding

Breast Cancer 1, Early Onset spielt in den folgenden Prozessen eine Rolle:

DNA repair – DNA replication – cell cycle – centrosome cycle – chordate embryonic development – dosage compensation, by inactivation of X chromosome – modification-dependent protein catabolic process – negative regulation of fatty acid biosynthetic process – response to DNA damage stimulus – chromosome segregation – double-strand break repair via homologous recombination – glucose metabolic process – negative regulation of transcription – oxidation reduction – positive regulation of protein ubiquitination – postreplication repair – DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator – DNA damage response, signal transduction resulting in induction of apoptosis – G2/M transition DNA damage checkpoint – androgen receptor signaling pathway – negative regulation of centriole replication – positive regulation of DNA repair – positive regulation of transcription, DNA-dependent – regulation of apoptosis – regulation of cell proliferation – regulation of transcription from RNA polymerase II promoter – regulation of transcription from RNA polymerase III promoter – response to estrogen stimulus – response to ionizing radiation – brain development – response to lipid – response to nutrient – response to organic substance – centrosome duplication – fatty acid biosynthetic process – lipid biosynthetic process – DNA recombination – response to gamma radiation

Breast Cancer 1, Early Onset ist wie folgt lokalisiert:

condensed chromosome – cytoplasm – intracellular – nucleus – BRCA1-A complex – BRCA1-BARD1 complex – gamma-tubulin ring complex – nucleoplasm – ribonucleoprotein complex – ubiquitin ligase complex – mitochondrial matrix – centrosome

Quelle: NCBI Entrez Gene, Gene Ontology