Die folgenden Gennamen und Gensymbole werden für Antigen BMI1 Polycomb Ring Finger Oncogene über verschiedene Spezies hinweg verwendet:

BMI1 polycomb ring finger oncogene (LOC100230513), BMI1 polycomb ring finger oncogene (LOC100358360), BMI1 polycomb ring finger oncogene (BMI1), Bmi1 polycomb ring finger oncogene (Bmi1), B lymphoma Mo-MLV insertion region 1 (bmi1)

Zu den weiteren Synonymen zählen:

PCGF4, RNF51, MGC12685, Bmi-1, Pcgf4, AW546694, psc1, pcgf4, wu:fb17g03, wu:fd18f06, BMI1, MGC134151

Auf Proteinebene tauchen folgende Bezeichner für Antigen BMI1 Polycomb Ring Finger Oncogene auf:

BMI1 polycomb ring finger oncogene – flvi-2/bmi-1 – oncogene BMI-1 – ring finger protein 51 – polycomb group protein Bmi1 – polycomb group ring finger 4 – B lymphoma Mo-MLV insertion region 1 homolog – murine leukemia viral (bmi-1) oncogene homolog – polycomb complex protein BMI-1 – OTTMUSP00000012215 – OTTMUSP00000012216 – OTTMUSP00000012217 – B lymphoma Mo-MLV insertion region 1 – polycomb group RING finger protein 4

BMI1 Polycomb Ring Finger Oncogene erfüllt eine Reihe von Funktionen:

metal ion binding – protein binding – zinc ion binding – chromatin binding – transcription repressor activity – ubiquitin-protein ligase activity – RING-like zinc finger domain binding

BMI1 Polycomb Ring Finger Oncogene spielt in den folgenden Prozessen eine Rolle:

chromatin modification – hemopoiesis – positive regulation of fibroblast proliferation – regulation of transcription – segment specification – brain development – cellular process – embryonic skeletal system development – embryonic skeletal system morphogenesis – histone acetylation – histone ubiquitination – humoral immune response – in utero embryonic development – negative regulation of apoptosis – negative regulation of transcription from RNA polymerase II promoter – positive regulation of B cell proliferation – positive regulation of immature T cell proliferation in the thymus – rostrocaudal neural tube patterning – skeletal system development – somatic stem cell division – transcription – positive regulation of ubiquitin-protein ligase activity – regulation of gene expression

BMI1 Polycomb Ring Finger Oncogene ist wie folgt lokalisiert:

cytoplasm – nucleus – PcG protein complex – nuclear body – ubiquitin ligase complex

Quelle: NCBI Entrez Gene, Gene Ontology