Die folgenden Gennamen und Gensymbole werden für Antigen BCL2-Like 1 über verschiedene Spezies hinweg verwendet:

BCL2-like 1 (BCL2L1), BCL2-like 1 (Bcl2l1), Bcl2-like 1 (Bcl2l1), BCL2-like 1 (bcl2l1), BCL2-like 1 (LOC100224900)

Zu den weiteren Synonymen zählen:

BCLX, BCL2L, Bcl-X, bcl-xL, bcl-xS, BCL-XL/S, DKFZp781P2092, BclX, Bcl2l, bcl-x, Bcl-XL, Bcl-Xs, Bcl(X)L, MGC99998, MGC113803, Bclx, bcl-X, Bcl-xl, BCL2L1, Bcl-xL, BCL-XL, bclx, xR11, bcl2l, bclxl, bcl-XL, bcl-xs, MGC69340, bcl-xl/s, bcl-xl

Auf Proteinebene tauchen folgende Bezeichner für Antigen BCL2-Like 1 auf:

BCL2-like 1 – OTTHUMP00000030550 – OTTMUSP00000016850 – B-cell leukemia/lymphoma x – anti-apoptosis regulatory protein – Bcl2-like 1 – B cell lymphoma 2 like – B cell lymphoma like X – BCL2-like protein 1 – apoptosis regulator Bcl-X – anti-apoptotic Bcl-xL – BCLX protein – Bcl-X

BCL2-Like 1 erfüllt eine Reihe von Funktionen:

identical protein binding – protein binding – protein heterodimerization activity – caspase inhibitor activity

BCL2-Like 1 spielt in den folgenden Prozessen eine Rolle:

anti-apoptosis – negative regulation of survival gene product expression – regulation of mitochondrial membrane permeability – regulation of mitochondrial membrane potential – release of cytochrome c from mitochondria – response to cytokine stimulus – apoptosis – cell proliferation – fertilization – germ cell development – growth – in utero embryonic development – male gonad development – negative regulation of apoptosis – negative regulation of neuron apoptosis – ovarian follicle development – positive regulation of anti-apoptosis – positive regulation of apoptosis – positive regulation of cell proliferation – regulation of apoptosis – response to cycloheximide – response to protein stimulus – response to radiation – spermatogenesis – response to hydrogen peroxide – response to hypoxia – response to inorganic substance – response to lead ion – response to organic cyclic substance – response to organic nitrogen – response to oxidative stress – response to peptide hormone stimulus – response to stress

BCL2-Like 1 ist wie folgt lokalisiert:

integral to membrane – internal side of plasma membrane – membrane – mitochondrial outer membrane – mitochondrion – nucleus – cytoplasm – cytosol – intracellular – mitochondrial membrane – mitochondrial part – integral to membrane of membrane fraction – mitochondrial envelope

Quelle: NCBI Entrez Gene, Gene Ontology