Die folgenden Gennamen und Gensymbole werden für Antigen B-Cell Leukemia/lymphoma 6 über verschiedene Spezies hinweg verwendet:

B-cell leukemia/lymphoma 6 (Bcl6)

Zu den weiteren Synonymen zählen:

Bcl5

Auf Proteinebene tauchen folgende Bezeichner für Antigen B-Cell Leukemia/lymphoma 6 auf:

B-cell lymphoma 6 protein homolog – B-cell leukemia/lymphoma 5

B-Cell Leukemia/lymphoma 6 erfüllt eine Reihe von Funktionen:

DNA binding – chromatin DNA binding – chromatin binding – metal ion binding – nucleic acid binding – protein binding – sequence-specific DNA binding – transcription repressor activity – zinc ion binding

B-Cell Leukemia/lymphoma 6 spielt in den folgenden Prozessen eine Rolle:

B cell differentiation – Rho protein signal transduction – T-helper 2 type immune response – actin cytoskeleton organization – cell morphogenesis – erythrocyte development – germinal center formation – negative regulation of Rho protein signal transduction – negative regulation of T-helper 2 cell differentiation – negative regulation of T-helper 2 type immune response – negative regulation of apoptosis – negative regulation of cell differentiation – negative regulation of cell proliferation – negative regulation of cell-matrix adhesion – negative regulation of isotype switching to IgE isotypes – negative regulation of mast cell cytokine production – negative regulation of transcription from RNA polymerase II promoter – positive regulation of B cell proliferation – positive regulation of cellular component movement – protein localization – regulation of Rho GTPase activity – regulation of cell proliferation – regulation of inflammatory response – regulation of memory T cell differentiation – regulation of transcription – spermatogenesis – transcription

B-Cell Leukemia/lymphoma 6 ist wie folgt lokalisiert:

intracellular – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology