Die folgenden Gennamen und Gensymbole werden für Antigen B-Cell CLL/lymphoma 3 über verschiedene Spezies hinweg verwendet:

B-cell CLL/lymphoma 3 (BCL3), B-cell leukemia/lymphoma 3 (Bcl3), B-cell CLL/lymphoma 9-like (BCL9L), B-cell CLL/lymphoma 3 (Bcl3), B-cell CLL/lymphoma 3 (LOC100356260)

Zu den weiteren Synonymen zählen:

BCL4, D19S37, Bcl-3, AI528691, BCL9-2, DLNB11, BCL3

Auf Proteinebene tauchen folgende Bezeichner für Antigen B-Cell CLL/lymphoma 3 auf:

B-cell CLL/lymphoma 3 – B-cell leukemia/lymphoma 3 – B-cell lymphoma 3-encoded protein – chronic lymphatic leukemia protein – B-cell lymphoma 3 protein homolog – OTTMUSP00000041182 – B-cell CLL/lymphoma 9-like – nuclear co-factor of beta-catenin signalling

B-Cell CLL/lymphoma 3 erfüllt eine Reihe von Funktionen:

protein binding, bridging – transcription factor activity – transcription factor binding – DNA binding – protein binding – sequence-specific DNA binding transcription factor activity – regulation of transcription

B-Cell CLL/lymphoma 3 spielt in den folgenden Prozessen eine Rolle:

DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis – I-kappaB kinase/NF-kappaB cascade – T-helper 1 type immune response – T-helper 2 cell differentiation – antimicrobial humoral response – defense response to bacterium – defense response to protozoan – extracellular matrix organization – follicular dendritic cell differentiation – germinal center formation – humoral immune response mediated by circulating immunoglobulin – maintenance of protein location in nucleus – marginal zone B cell differentiation – negative regulation of apoptosis – negative regulation of interleukin-8 biosynthetic process – negative regulation of transcription – negative regulation of tumor necrosis factor biosynthetic process – positive regulation of interferon-gamma production – positive regulation of interleukin-10 biosynthetic process – positive regulation of transcription – positive regulation of transcription from RNA polymerase II promoter – positive regulation of translation – protein import into nucleus, translocation – regulation of DNA binding – regulation of NF-kappaB import into nucleus – response to DNA damage stimulus – response to UV-C – response to virus – spleen development – regulation of transcription – transcription – nucleus

B-Cell CLL/lymphoma 3 ist wie folgt lokalisiert:

Bcl3-Bcl10 complex – Bcl3/NF-kappaB2 complex – cytoplasm – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology