Die folgenden Gennamen und Gensymbole werden für Antigen Aurora Kinase B über verschiedene Spezies hinweg verwendet:

aurora kinase B (AURKB), aurora kinase C (Aurkc), aurora kinase B (Aurkb), IplI-aurora-like kinase (ial), aurora kinase B (aurkb), serine/threonine kinase a (stka)

Zu den weiteren Synonymen zählen:

AIK2, AIM1, ARK2, AurB, IPL1, STK5, AIM-1, STK12, aurkb-sv1, aurkb-sv2, AIE1, AIK3, Stk13, Aik2, Aim1, Ark2, Stk5, AIRK2, STK-1, Stk12, AL022959, DmAIRK2, DmAurB, DmAuroraB, IAL, IAL1, aurora B, DmelCG6620, CG6620, AURKB, MGC142782, aik2, aim1, ark2, ipl1, stk5, aim-1, stk12, Aurora-B, fa09g06, MGC85918, CHUNP6896, wu:fa09g06, aurkb

Auf Proteinebene tauchen folgende Bezeichner für Antigen Aurora Kinase B auf:

aurora kinase B – aurora-1 – aurora-B – aurora kinase B-Sv1 – aurora kinase B-Sv2 – serine/threonine kinase 12 – aurora kinase C – aurora B – serine/threonine kinase 13 (aurora/IPL-like) – OTTMUSP00000006162 – OTTMUSP00000006163 – aurora-related kinase 2 – serine/threonine kinase 5 – IplI-aurora-like kinase – CG6620-PA – ial-PA – AURORA-like – aurora B kinase – auroraB – dAurora B – Serine/threonine-protein kinase 12 – serine/threonine-protein kinase 12 – serine/threonine-protein kinase 12-like

Aurora Kinase B erfüllt eine Reihe von Funktionen:

ATP binding – magnesium ion binding – nucleotide binding – protein binding – protein serine/threonine kinase activity – transferase activity – kinase activity – protein kinase activity – metal ion binding – methyltransferase activity – nucleic acid binding

Aurora Kinase B spielt in den folgenden Prozessen eine Rolle:

cell cycle – cytokinesis – mitosis – protein amino acid phosphorylation – protein localization to kinetochore – cell division – attachment of spindle microtubules to kinetochore – chromatin organization – histone phosphorylation – mitotic chromosome condensation – mitotic sister chromatid segregation – mitotic spindle organization – methylation – chromosome segregation – microtubule cytoskeleton organization – multicellular organismal development

Aurora Kinase B ist wie folgt lokalisiert:

chromosome – chromosome passenger complex – condensed chromosome, centromeric region – midbody – nucleus – spindle – chromosome, centromeric region – cytoplasm – cytoskeleton – kinetochore – spindle midzone

Quelle: NCBI Entrez Gene, Gene Ontology