Die folgenden Gennamen und Gensymbole werden für Antigen Aprataxin über verschiedene Spezies hinweg verwendet:

aprataxin (APTX), aprataxin (Aptx), forkhead-associated domain histidine-triad like protein (aptx), FHA-HIT protein (aptx), aprataxin (aptx), FHA-HIT (aptx), FHA-HIT long isoform (aptx), aprataxin (CpipJ_CPIJ001673), aprataxin (LOC100284636)

Zu den weiteren Synonymen zählen:

AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT, MGC1072, FLJ20157, AA388047, 2410016G21Rik, APTX, MGC133769, aptx, MGC131296, LOC100284636, APRATAXIN-like, T10O8.20, T10O8_20

Auf Proteinebene tauchen folgende Bezeichner für Antigen Aprataxin auf:

aprataxin – OTTMUSP00000006927 – OTTMUSP00000006929 – forkhead-associated domain histidine-triad like – FHA-HIT – forkhead-associated domain histidine triad-like protein – aprataxin-like

Aprataxin erfüllt eine Reihe von Funktionen:

DNA 5'-adenosine monophosphate hydrolase activity – chromatin binding – damaged DNA binding – double-stranded DNA binding – double-stranded RNA binding – hydrolase activity – metal ion binding – phosphoglycolate phosphatase activity – protein N-terminus binding – zinc ion binding – DNA binding – catalytic activity – molecular_function – adenylylsulfatase activity – sequence-specific DNA binding transcription factor activity

Aprataxin spielt in den folgenden Prozessen eine Rolle:

cell death – regulation of protein stability – response to DNA damage stimulus – response to hydrogen peroxide – single strand break repair – DNA ligation – DNA repair – biological_process – purine ribonucleotide metabolic process – regulation of transcription, DNA-dependent – sulfur compound metabolic process

Aprataxin ist wie folgt lokalisiert:

chromatin – intracellular – nucleolus – nucleoplasm – nucleus – cellular_component – chloroplast

Quelle: NCBI Entrez Gene, Gene Ontology