Die folgenden Gennamen und Gensymbole werden für Antigen Apoptotic Peptidase Activating Factor 1 über verschiedene Spezies hinweg verwendet:

apoptotic peptidase activating factor 1 (APAF1), apoptotic peptidase activating factor 1 (Apaf1), Apaf-1-related-killer (Ark), apoptotic peptidase activating factor 1 (apaf1)

Zu den weiteren Synonymen zählen:

CED4, APAF-1, DKFZp781B1145, fog, Apaf-1, Apaf1l, KIAA0413, mKIAA0413, 6230400I06Rik, ARK, Apaf1, D-Apaf-1, DARK, Dapaf-1, Dapaf-1/HAC-1, Dark/Apaf-I, Dark/Dapaf-1/HAC1, Dark/Hac-1/dApaf-1, Hac-1, Hac-1/Dark, Hac1, T1, anon-53Fa, arc, dApaf-1/DARK/HAC-1, dApaf1, dapaf, dapaf-1L, dapaf-1S, dark/dapaf-1/hac-1, DmelCG6829, CG6829, apaf-1, MGC80868, APAF1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Apoptotic Peptidase Activating Factor 1 auf:

apoptotic peptidase activating factor 1 – apoptotic protease activating factor 1 – forebrain overgrowth – Apaf-1-related-killer, isoform B – CG6829-PB – Ark-PB – Apaf-1 related killer – drosophila Apaf-1-related killer – transcription unit 1 – Apaf-1-related-killer, isoform A – CG6829-PA – Ark-PA – apoptotic protease-activating factor 1 – apaf-1 – apoptotic protease-activating factor 1-like

Apoptotic Peptidase Activating Factor 1 erfüllt eine Reihe von Funktionen:

ATP binding – caspase activator activity – nucleotide binding – protein binding – apoptotic protease activator activity – identical protein binding

Apoptotic Peptidase Activating Factor 1 spielt in den folgenden Prozessen eine Rolle:

activation of caspase activity by cytochrome c – defense response – nervous system development – regulation of apoptosis – DNA fragmentation involved in apoptosis – activation of caspase activity – apoptosis – brain development – forebrain development – multicellular organismal development – neural tube closure – neuron apoptosis – proteolysis – central nervous system formation – histolysis – induction of apoptosis – programmed cell death – regulation of retinal cell programmed cell death – response to DNA damage stimulus – response to gamma radiation – salivary gland cell autophagic cell death – sensory organ development – sperm individualization – DNA fragmentation involved in apoptotic nuclear change – aging – cardiac muscle cell apoptosis – cell differentiation – cellular response to transforming growth factor beta stimulus – glial cell apoptosis – positive regulation of peptidase activity – protein homooligomerization – response to hypoxia – response to nutrient

Apoptotic Peptidase Activating Factor 1 ist wie folgt lokalisiert:

cytoplasm – cytosol – intracellular – membrane – nucleus – soluble fraction – apoptosome

Quelle: NCBI Entrez Gene, Gene Ontology