Die folgenden Gennamen und Gensymbole werden für Antigen Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 über verschiedene Spezies hinweg verwendet:

apoptosis-inducing factor, mitochondrion-associated, 3 (AIFM3), apoptosis-inducing factor, mitochondrion-associated, 3 (aifm3), apoptosis-inducing factor, mitochondrion-associated, 3 (CH73-13B6.1), apoptosis-inducing factor, mitochondrion-associated, 3 (LOC100227335), apoptosis-inducing factor, mitochondrion-associated, 3 (LOC100345791)

Zu den weiteren Synonymen zählen:

AIFL, FLJ30473, FLJ45137, nfrl-A, MGC84340, AIFM3, MGC128925, LOC100150876

Auf Proteinebene tauchen folgende Bezeichner für Antigen Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 auf:

apoptosis-inducing factor, mitochondrion-associated, 3 – OTTHUMP00000198535 – OTTHUMP00000198536 – apoptosis-inducing factor like – neurula-specific ferredoxin reductase-like protein – apoptosis-inducing factor, mitochondrion-associated 3 – novel protein similar to vertebrate apoptosis-inducing factor, mitochondrion-associated, 3 (AIFM3) – apoptosis-inducing factor 3-like

Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 erfüllt eine Reihe von Funktionen:

2 iron, 2 sulfur cluster binding – FAD binding – caspase activator activity – electron carrier activity – iron ion binding – metal ion binding – oxidoreductase activity

Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 spielt in den folgenden Prozessen eine Rolle:

activation of caspase activity by cytochrome c – apoptosis – cell redox homeostasis – electron transport chain – induction of apoptosis – mitochondrial depolarization – transport – oxidation reduction

Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 ist wie folgt lokalisiert:

cytoplasm – cytosol – endoplasmic reticulum – mitochondrial inner membrane – mitochondrion – nucleus – plasma membrane

Quelle: NCBI Entrez Gene, Gene Ontology