Die folgenden Gennamen und Gensymbole werden für Antigen Apolipoprotein B48 über verschiedene Spezies hinweg verwendet:

apolipoprotein B (including Ag(x) antigen) (APOB)

Zu den weiteren Synonymen zählen:

FLDB, LDLCQ4

Auf Proteinebene tauchen folgende Bezeichner für Antigen Apolipoprotein B48 auf:

apolipoprotein B – apoB-48 – apoB-100 – apolipoprotein B48

Apolipoprotein B48 erfüllt eine Reihe von Funktionen:

cholesterol transporter activity – enzyme binding – heparin binding – lipid transporter activity – low-density lipoprotein receptor binding – phospholipid binding – protein heterodimerization activity

Apolipoprotein B48 spielt in den folgenden Prozessen eine Rolle:

artery morphogenesis – cholesterol homeostasis – cholesterol metabolic process – cholesterol transport – fertilization – in utero embryonic development – lipid catabolic process – lipid transport – lipoprotein biosynthetic process – lipoprotein catabolic process – lipoprotein transport – low-density lipoprotein particle clearance – low-density lipoprotein particle remodeling – nervous system development – positive regulation of cholesterol storage – positive regulation of macrophage derived foam cell differentiation – post-embryonic development – regulation of cholesterol biosynthetic process – sperm motility – spermatogenesis – steroid metabolic process – triglyceride catabolic process – triglyceride mobilization – very-low-density lipoprotein particle assembly

Apolipoprotein B48 ist wie folgt lokalisiert:

chylomicron remnant – clathrin-coated endocytic vesicle membrane – endoplasmic reticulum – endoplasmic reticulum lumen – endosome lumen – endosome membrane – extracellular region – intermediate-density lipoprotein particle – low-density lipoprotein particle – mature chylomicron – microsome – plasma membrane – very-low-density lipoprotein particle

Quelle: NCBI Entrez Gene, Gene Ontology