Die folgenden Gennamen und Gensymbole werden für Antigen Apolipoprotein A-IV über verschiedene Spezies hinweg verwendet:

apolipoprotein A-IV (APOA4), apolipoprotein A-IV (Apoa4), apolipoprotein A-IV (apoa4), apolipoprotein A4 (apoa4), zgc:112992 (zgc:112992)

Zu den weiteren Synonymen zählen:

MGC142154, MGC142156, Apoa-4, MGC122983, wu:fb64f03, wu:fb66f09, zgc:122983, APOA4, APOAIV, myh11, MGC89243, MGC127813

Auf Proteinebene tauchen folgende Bezeichner für Antigen Apolipoprotein A-IV auf:

apolipoprotein A-IV – fb66f09 – apolipoprotein A4 – apolipoprotein A-IV-like

Apolipoprotein A-IV erfüllt eine Reihe von Funktionen:

antioxidant activity – cholesterol transporter activity – copper ion binding – eukaryotic cell surface binding – lipid binding – lipid transporter activity – phosphatidylcholine binding – phosphatidylcholine-sterol O-acyltransferase activator activity – protein homodimerization activity

Apolipoprotein A-IV spielt in den folgenden Prozessen eine Rolle:

cholesterol efflux – cholesterol homeostasis – cholesterol metabolic process – chylomicron assembly – chylomicron remodeling – high-density lipoprotein particle remodeling – hydrogen peroxide catabolic process – innate immune response in mucosa – leukocyte adhesion – lipid homeostasis – lipid transport – lipoprotein metabolic process – multicellular organismal lipid catabolic process – negative regulation of plasma lipoprotein oxidation – phosphatidylcholine metabolic process – phospholipid efflux – positive regulation of cholesterol esterification – positive regulation of fatty acid biosynthetic process – positive regulation of lipoprotein lipase activity – positive regulation of triglyceride catabolic process – protein-lipid complex assembly – regulation of cholesterol transport – removal of superoxide radicals – response to lipid hydroperoxide – reverse cholesterol transport – very-low-density lipoprotein particle remodeling – regulation of intestinal cholesterol absorption – transport – axon regeneration in the peripheral nervous system – response to food

Apolipoprotein A-IV ist wie folgt lokalisiert:

chylomicron – endoplasmic reticulum lumen – extracellular region – extracellular space – high-density lipoprotein particle – very-low-density lipoprotein particle

Quelle: NCBI Entrez Gene, Gene Ontology