Die folgenden Gennamen und Gensymbole werden für Antigen Apolipoprotein A-II über verschiedene Spezies hinweg verwendet:

apolipoprotein A-II (APOA2), apolipoprotein A-II (Apoa2), apolipoprotein A-II (apoa2), apolipoprotein A-II (LOC100339653)

Zu den weiteren Synonymen zählen:

Alp-2, Hdl-1, ApoAII, Apoa-2, ApoA-II, APOAII, APOA2, MGC137013, apoa2

Auf Proteinebene tauchen folgende Bezeichner für Antigen Apolipoprotein A-II auf:

apolipoprotein A-II – OTTMUSP00000024197 – OTTMUSP00000024198 – OTTMUSP00000024207 – OTTMUSP00000024208

Apolipoprotein A-II erfüllt eine Reihe von Funktionen:

apolipoprotein receptor binding – cholesterol binding – cholesterol transporter activity – high-density lipoprotein binding – high-density lipoprotein receptor binding – lipase inhibitor activity – lipid transporter activity – phosphatidylcholine binding – phosphatidylcholine-sterol O-acyltransferase activator activity – protein binding – protein heterodimerization activity – protein homodimerization activity – lipid binding – molecular_function – triglyceride binding

Apolipoprotein A-II spielt in den folgenden Prozessen eine Rolle:

cholesterol efflux – cholesterol homeostasis – cholesterol metabolic process – diacylglycerol catabolic process – high-density lipoprotein particle assembly – high-density lipoprotein particle clearance – high-density lipoprotein particle remodeling – interspecies interaction between organisms – lipid transport – lipoprotein metabolic process – low-density lipoprotein particle remodeling – negative regulation of cholesterol import – negative regulation of cholesterol transporter activity – negative regulation of cytokine secretion during immune response – negative regulation of lipase activity – negative regulation of lipid catabolic process – negative regulation of very-low-density lipoprotein particle remodeling – phosphatidylcholine biosynthetic process – phospholipid catabolic process – phospholipid efflux – positive regulation of cholesterol esterification – positive regulation of interleukin-8 biosynthetic process – positive regulation of lipid catabolic process – protein folding – regulation of intestinal cholesterol absorption – regulation of protein stability – response to glucose stimulus – reverse cholesterol transport – triglyceride metabolic process – triglyceride-rich lipoprotein particle remodeling – beta-glucoside transport – fatty acid metabolic process – transport – acute inflammatory response – cholesterol transport – organ regeneration – response to drug – response to estrogen stimulus – response to glucocorticoid stimulus – defense response to bacterium

Apolipoprotein A-II ist wie folgt lokalisiert:

chylomicron – endoplasmic reticulum lumen – extracellular region – extracellular space – spherical high-density lipoprotein particle – very-low-density lipoprotein particle – high-density lipoprotein particle – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology