Die folgenden Gennamen und Gensymbole werden für Antigen Apolipoprotein A-I über verschiedene Spezies hinweg verwendet:

apolipoprotein A-I (APOA1), apolipoprotein A-I-like (LOC100386212), apolipoprotein A-I (apoa1), apolipoprotein A-I (Apoa1), apolipoprotein A1 (ApoA1), apolipoprotein A-I (apoa-i), apolipoprotein A-I (LOC100009253), apolipoprotein A-I (LOC100136573), Apolipoprotein A-I (apoa1)

Zu den weiteren Synonymen zählen:

APOA1, MGC117399, Sep2, Alp-1, Ltw-1, Sep-1, Sep-2, Apoa-1, Brp-14, Lvtw-1, MGC102525, apoA-I, apoa, cb49, MGC103718, wu:fb33f01, zgc:103718, MGC64335, ApoA1, MGC89745, apoa-i, LOC100009253, ApoA-I, LOC100136573, apoa1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Apolipoprotein A-I auf:

apolipoprotein A-I – apolipoprotein A-I-like – apolipoprotein A-I preproprotein – OTTHUMP00000069346 – OTTHUMP00000069347 – OTTHUMP00000069348 – apolipoprotein A-1 – preproapolipoprotein A-I – etID32161.5 – etID309895.5 – apolipoprotein A1 – apolipoprotein AI (put.); putative – apo-AI – apoA-I – Apolipoprotein A-I

Apolipoprotein A-I erfüllt eine Reihe von Funktionen:

apolipoprotein A-I receptor binding – beta-amyloid binding – cholesterol binding – cholesterol transporter activity – enzyme binding – high-density lipoprotein receptor binding – identical protein binding – phosphatidylcholine-sterol O-acyltransferase activator activity – phospholipid binding – high-density lipoprotein binding – lipid binding – lipid transporter activity – lipoprotein binding – protein binding – enzyme inhibitor activity – phospholipid transporter activity

Apolipoprotein A-I spielt in den folgenden Prozessen eine Rolle:

Cdc42 protein signal transduction – G-protein coupled receptor protein signaling pathway – cholesterol efflux – cholesterol homeostasis – cholesterol import – cholesterol metabolic process – high-density lipoprotein particle assembly – high-density lipoprotein particle clearance – lipid metabolic process – lipid transport – lipoprotein metabolic process – negative regulation of cytokine secretion during immune response – negative regulation of interleukin-1 beta secretion – negative regulation of very-low-density lipoprotein particle remodeling – phosphatidylcholine biosynthetic process – phospholipid efflux – positive regulation of cholesterol esterification – positive regulation of hydrolase activity – protein stabilization – reverse cholesterol transport – steroid metabolic process – adrenal gland development – axon regeneration – blood vessel endothelial cell migration – cholesterol biosynthetic process – cholesterol transport – endothelial cell proliferation – glucocorticoid metabolic process – lipid storage – lipoprotein biosynthetic process – negative regulation of hydrolase activity – phospholipid metabolic process – positive regulation of transferase activity – protein localization – regulation of intestinal cholesterol absorption – regulation of protein amino acid phosphorylation – transport – axon regeneration in the peripheral nervous system – negative regulation of catalytic activity – organ regeneration – phospholipid transport – response to drug – response to estrogen stimulus – response to nutrient

Apolipoprotein A-I ist wie folgt lokalisiert:

cytoplasmic vesicle – endocytic vesicle – endoplasmic reticulum lumen – extracellular region – plasma membrane – secretory granule – spherical high-density lipoprotein particle – very-low-density lipoprotein particle – extracellular space – high-density lipoprotein particle – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology