Die folgenden Gennamen und Gensymbole werden für Antigen Annexin A1 über verschiedene Spezies hinweg verwendet:

annexin A1 (ANXA1), annexin A1 (Anxa1), annexin A1a (anxa1a), annexin A1 (anxa1), ANNAT1 (ANNEXIN ARABIDOPSIS 1); ATP binding / calcium ion binding / calcium-dependent phospholipid binding / copper ion binding / peroxidase/ protein homodimerization (ANNAT1), Annexin A1 (anxa1), annexin A1 (LOC100222491), annexin A1 (LOC100335033)

Zu den weiteren Synonymen zählen:

ANX1, LPC1, Lpc1, Anx-1, Lpc-1, Anx-A1, C430014K04Rik, p35, Anx1, ANXA1, anx1a, anxa1, wu:fa01d11, wu:fa05d11, wu:fk69h01, MGC64363, anx1, lpc1, MGC76270, MGC89164, ANNEXIN, ANNEXIN A1, ANNEXIN ARABIDOPSIS 1, ATOXY5, F14D7.2, F14D7_2, OXY5, DKFZp468O0210

Auf Proteinebene tauchen folgende Bezeichner für Antigen Annexin A1 auf:

annexin I – lipocortin I – OTTHUMP00000021475 – annexin I (lipocortin I) – annexin A1 – lipocortin 1 – Annexin 1 (p35) (Lipocortin 1) – ANX Ia – annexin 1a – calcium-dependent membrane binding protein annexin I – ANNAT1 (ANNEXIN ARABIDOPSIS 1); ATP binding / calcium ion binding / calcium-dependent phospholipid binding / copper ion binding / peroxidase/ protein homodimerization – annexin-1 – calpactin-2 – calpactin II – lipocortin-1 – Annexin A1 – p35 – chromobindin-9 – phospholipase A2 inhibitory protein – annexin A1-like

Annexin A1 erfüllt eine Reihe von Funktionen:

calcium ion binding – calcium-dependent phospholipid binding – phospholipase A2 inhibitor activity – protein binding, bridging – receptor binding – structural molecule activity – phospholipase inhibitor activity – protein binding – phospholipid binding – protein homodimerization activity – single-stranded DNA binding – single-stranded RNA binding – ATP binding – copper ion binding – peroxidase activity – zinc ion binding

Annexin A1 spielt in den folgenden Prozessen eine Rolle:

anti-apoptosis – arachidonic acid secretion – cell cycle – cell motion – cell surface receptor linked signal transduction – inflammatory response – keratinocyte differentiation – lipid metabolic process – peptide cross-linking – regulation of cell proliferation – signal transduction – cellular response to hydrogen peroxide – endocrine pancreas development – estrous cycle phase – gliogenesis – hepatocyte differentiation – insulin secretion – negative regulation of acute inflammatory response – negative regulation of apoptosis – negative regulation of protein secretion – positive regulation of apoptosis – positive regulation of prostaglandin biosynthetic process – response to X-ray – response to corticosteroid stimulus – response to drug – response to estradiol stimulus – response to glucocorticoid stimulus – response to hormone stimulus – response to interleukin-1 – response to organic cyclic substance – response to peptide hormone stimulus – response to abscisic acid stimulus – response to cadmium ion – response to osmotic stress – response to oxidative stress

Annexin A1 ist wie folgt lokalisiert:

basolateral plasma membrane – cilium – cornified envelope – cytoplasm – nucleus – sarcolemma – cell projection – membrane – plasma membrane – extracellular space – mitochondrial membrane – protein complex – apoplast – cell wall – chloroplast – chloroplast stroma – cytosol – mitochondrion – thylakoid – vacuole

Quelle: NCBI Entrez Gene, Gene Ontology