Die folgenden Gennamen und Gensymbole werden für Antigen Angiotensin II Receptor, Type 2 über verschiedene Spezies hinweg verwendet:

angiotensin II receptor, type 2 (AGTR2), angiotensin II receptor, type 2 (Agtr2), zgc:113016 (zgc:113016), angiotensin II receptor, type 2 (agtr2), angiotensin II subtype 2 receptor (AT2), angiotensin 2 receptor, type 2 (agtr2)

Zu den weiteren Synonymen zählen:

AT2, ATGR2, MRX88, AI316812, AW107640, AT2R, AT2-R, AT₂R, AGTR2, at2, at2r, atgr2, mrx88, MGC147625

Auf Proteinebene tauchen folgende Bezeichner für Antigen Angiotensin II Receptor, Type 2 auf:

angiotensin II receptor, type 2 – angiotensin receptor 2 – AT2 receptor – OTTMUSP00000018718 – Angiotensin receptor 2 – angiotensin II type 2 receptor – type-2 angiotensin II receptor – angiotensin type II receptor – type-2 angiotensin II receptor-like – angiotensin II subtype 2 receptor – Type-2 angiotensin II receptor – angiotensin II subtype 2 receptor, AT2 – angiotensin 2 receptor, type 2

Angiotensin II Receptor, Type 2 erfüllt eine Reihe von Funktionen:

G-protein coupled receptor activity – angiotensin type II receptor activity – protein binding – receptor activity – receptor antagonist activity – signal transducer activity – G-protein alpha-subunit binding – peptide hormone binding – transcription factor binding

Angiotensin II Receptor, Type 2 spielt in den folgenden Prozessen eine Rolle:

G-protein coupled receptor protein signaling pathway – G-protein signaling, coupled to cGMP nucleotide second messenger – behavior – blood vessel remodeling – brain development – brain renin-angiotensin system – negative regulation of blood vessel endothelial cell migration – negative regulation of cell growth – negative regulation of heart rate – negative regulation of nerve growth factor receptor signaling pathway – nitric oxide mediated signal transduction – positive regulation of apoptosis – positive regulation of nitric oxide biosynthetic process – positive regulation of nitric-oxide synthase activity – positive regulation of phosphoprotein phosphatase activity – positive regulation of vasodilation – protein kinase cascade – regulation of blood pressure – regulation of systemic arterial blood pressure by circulatory renin-angiotensin – vasodilation by angiotensin involved in regulation of systemic arterial blood pressure – negative regulation of neuron apoptosis – signal transduction – cellular sodium ion homeostasis – natriuresis – neuron differentiation – regulation of transcription factor import into nucleus

Angiotensin II Receptor, Type 2 ist wie folgt lokalisiert:

integral to plasma membrane – plasma membrane – integral to membrane – membrane – perinuclear region of cytoplasm

Quelle: NCBI Entrez Gene, Gene Ontology