Die folgenden Gennamen und Gensymbole werden für Antigen Androgen Receptor über verschiedene Spezies hinweg verwendet:

androgen receptor (AR), androgen receptor (Ar), androgen receptor (ar)

Zu den weiteren Synonymen zählen:

KD, AIS, TFM, DHTR, SBMA, HYSP1, NR3C4, SMAX1, HUMARA, Tfm, AW320017, Andr, AR, DKFZp468G2216

Auf Proteinebene tauchen folgende Bezeichner für Antigen Androgen Receptor auf:

androgen receptor – dihydrotestosterone receptor – OTTMUSP00000019597 – testicular feminization – androgen receptor (Testicular feminization), same as Tfm – androgen receptor AR – androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) – Ar beta – prostate androgen receptor – nuclear receptor subfamily 3 group C member 4

Androgen Receptor erfüllt eine Reihe von Funktionen:

androgen binding – androgen receptor activity – metal ion binding – protein dimerization activity – receptor activity – receptor binding – sequence-specific DNA binding – transcription factor activity – zinc ion binding – DNA binding – lipid binding – protein binding – steroid binding – steroid hormone receptor activity – transcription activator activity – ligand-dependent nuclear receptor activity – transcription regulator activity

Androgen Receptor spielt in den folgenden Prozessen eine Rolle:

androgen receptor signaling pathway – cell death – cell growth – cell proliferation – cell-cell signaling – in utero embryonic development – male gonad development – male somatic sex determination – positive regulation of transcription from RNA polymerase II promoter – prostate gland development – regulation of catalytic activity – sex differentiation – signal transduction – transport – activation of prostate induction by androgen receptor signaling pathway – cellular process – epithelial cell differentiation involved in prostate gland development – lateral sprouting involved in mammary gland duct morphogenesis – mammary gland alveolus development – morphogenesis of an epithelial fold – negative regulation of epithelial cell proliferation – organ formation – positive regulation of MAPKKK cascade – positive regulation of estrogen receptor signaling pathway – positive regulation of insulin-like growth factor receptor signaling pathway – prostate gland epithelium morphogenesis – prostate gland growth – regulation of developmental growth – regulation of gene expression – regulation of prostatic bud formation – regulation of transcription – regulation of transcription from RNA polymerase II promoter – regulation of transcription, DNA-dependent – reproductive structure development – tertiary branching involved in mammary gland duct morphogenesis – transcription – male sex differentiation – response to insulin stimulus

Androgen Receptor ist wie folgt lokalisiert:

cytoplasm – nucleus – axon – dendrite

Quelle: NCBI Entrez Gene, Gene Ontology