Die folgenden Gennamen und Gensymbole werden für Antigen Amyotrophic Lateral Sclerosis 2 (Juvenile) über verschiedene Spezies hinweg verwendet:

amyotrophic lateral sclerosis 2 (juvenile) (ALS2), amyotrophic lateral sclerosis 2 (juvenile) homolog (human) (Als2), amyotrophic lateral sclerosis 2a (juvenile) (als2a), alsin (CpipJ_CPIJ008258), alsin (CpipJ_CPIJ008260), alsin (LOC100345931), alsin-like (LOC100436721)

Zu den weiteren Synonymen zählen:

ALSJ, PLSJ, IAHSP, ALS2CR6, FLJ31851, KIAA1563, MGC87187, als2, si:dkey-33m14.1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Amyotrophic Lateral Sclerosis 2 (Juvenile) auf:

alsin – amyotrophic lateral sclerosis 2 (juvenile) homolog – amyotrophic lateral sclerosis 2a (juvenile) – alsin 2 – amyotrophic lateral sclerosis 2 (juvenile) – alsin-like

Amyotrophic Lateral Sclerosis 2 (Juvenile) erfüllt eine Reihe von Funktionen:

Rab GTPase binding – Rab guanyl-nucleotide exchange factor activity – Rac guanyl-nucleotide exchange factor activity – Ran guanyl-nucleotide exchange factor activity – guanyl-nucleotide exchange factor activity – protein binding – protein homodimerization activity – protein serine/threonine kinase activator activity – molecular_function

Amyotrophic Lateral Sclerosis 2 (Juvenile) spielt in den folgenden Prozessen eine Rolle:

cell death – endosome organization – neuron projection morphogenesis – positive regulation of Rac GTPase activity – positive regulation of Rac protein signal transduction – positive regulation of protein kinase activity – regulation of Rho protein signal transduction – regulation of endosome size – Rac protein signal transduction – axonogenesis – behavioral fear response – endosome transport – in utero embryonic development – locomotory behavior – neuromuscular junction development – protein localization – receptor recycling – regulation of Rab GTPase activity – response to oxidative stress – synaptic transmission, glutamatergic – vesicle organization

Amyotrophic Lateral Sclerosis 2 (Juvenile) ist wie folgt lokalisiert:

centrosome – cytosol – dendrite – early endosome – intracellular – lamellipodium – protein complex – ruffle – vesicular fraction – axon – cell soma – cytoplasm – dendritic spine – growth cone – membrane – microsome – postsynaptic density – synaptosome

Quelle: NCBI Entrez Gene, Gene Ontology