Die folgenden Gennamen und Gensymbole werden für Antigen Amphiregulin über verschiedene Spezies hinweg verwendet:

amphiregulin (AREG), amphiregulin (Areg)

Zu den weiteren Synonymen zählen:

AR, SDGF, CRDGF, MGC13647, Sdgf, AREG, AREGB, MGC152310

Auf Proteinebene tauchen folgende Bezeichner für Antigen Amphiregulin auf:

amphiregulin – schwannoma-derived growth factor – colorectum cell-derived growth factor – amphiregulin long form – amphiregulin (schwannoma-derived growth factor) – amphiregulin B

Amphiregulin erfüllt eine Reihe von Funktionen:

cytokine activity – growth factor activity – epidermal growth factor receptor binding

Amphiregulin spielt in den folgenden Prozessen eine Rolle:

G-protein coupled receptor protein signaling pathway – cell proliferation – cell-cell signaling – epidermal growth factor receptor signaling pathway – positive regulation of DNA replication – dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis – epithelial cell proliferation involved in mammary gland duct elongation – mammary gland alveolus development – mammary gland branching involved in thelarche – response to estradiol stimulus – central nervous system development – glial cell proliferation – negative regulation of osteoblast differentiation – neuron projection development – positive regulation of cell proliferation – positive regulation of phosphorylation – response to cAMP – response to glucocorticoid stimulus – response to hydrogen peroxide – response to organic cyclic substance – response to peptide hormone stimulus

Amphiregulin ist wie folgt lokalisiert:

cell surface – extracellular space – integral to membrane – membrane – cytoplasm – intracellular – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology