Die folgenden Gennamen und Gensymbole werden für Antigen Adrenergic, Beta, Receptor Kinase 1 über verschiedene Spezies hinweg verwendet:

adrenergic, beta-1-, receptor (ADRB1), adrenergic, beta-1-, receptor (Adrb1), adrenergic, beta, receptor kinase 1 (Adrbk1), adrenergic receptor kinase, beta 1 (Adrbk1), adrenergic, beta, receptor kinase 1 (ADRBK1), beta-1 adrenergic receptor (adrb1), adrenergic, beta-1-, receptor (adrb1), beta-adrenergic receptor kinase 1 (Tsp_00497), adrenergic, beta, receptor kinase 1 (LOC100227701), adrenergic receptor, beta 1 (Adrb1), adrenergic, beta, receptor kinase 1 (adrbk1)

Zu den weiteren Synonymen zählen:

RHR, B1AR, ADRB1R, BETA1AR, RATB1AR, Grk2, BARK1, GRK-2, GRK2, Bark-1, Adrbk-1, betaARK1, ADRB1, ADRBK1, adrb1, X-Beta1AR, BAR1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Adrenergic, Beta, Receptor Kinase 1 auf:

beta-1-adrenergic receptor – adrenergic, beta-1-, receptor – adrenergic receptor, beta 1 – beta 1-adrenergic receptor beta 1-AR – beta-adrenergic receptor kinase 1 – adrenergic receptor kinase, beta 1 – G-protein-coupled receptor kinase 2 – beta-adrenergic receptor kinase 1 beta ARK1 – beta ARK – beta ARK1 – beta-AR kinase-1 – beta-adrenergic receptor kinase-1 – beta 1 adrenergic receptor – beta-1 adrenoceptor – beta-1 adrenoreceptor – beta 1 adrenergic protein – Beta-1 adrenergic receptor – beta-1 adrenergic receptor – beta 1-adrenergic receptor – G-protein-coupled hormone receptor – adrenergic, beta, receptor kinase 1 – beta adrenergic receptor kinase 1 – tripartite motif-containing 75 – beta1-adrenergic G-protein-coupled receptor – beta-adrenergic receptor kinase 1-like

Adrenergic, Beta, Receptor Kinase 1 erfüllt eine Reihe von Funktionen:

G-protein coupled receptor activity – beta1-adrenergic receptor activity – protein binding – receptor activity – PDZ domain binding – adrenoceptor activity – dopamine binding – drug binding – epinephrine binding – norepinephrine binding – ATP binding – G-protein coupled receptor kinase activity – beta-2 adrenergic receptor binding – beta-adrenergic receptor kinase activity – nucleotide binding – protein kinase activity – protein serine/threonine kinase activity – signal transducer activity – transferase activity – kinase activity – cysteine-type endopeptidase activity

Adrenergic, Beta, Receptor Kinase 1 spielt in den folgenden Prozessen eine Rolle:

G-protein coupled receptor protein signaling pathway – activation of adenylate cyclase activity by G-protein signaling pathway – brown fat cell differentiation – diet induced thermogenesis – fear response – heat generation – negative regulation of multicellular organism growth – positive regulation of heart rate by epinephrine-norepinephrine – positive regulation of the force of heart contraction by epinephrine-norepinephrine – response to cold – signal transduction – vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure – regulation of synaptic plasticity – aging – cardiac muscle contraction – desensitization of G-protein coupled receptor protein signaling pathway – heart development – negative regulation of G-protein coupled receptor protein signaling pathway – negative regulation of striated muscle contraction – negative regulation of the force of heart contraction by chemical signal – peptidyl-serine phosphorylation – peptidyl-threonine phosphorylation – positive regulation of catecholamine secretion – protein amino acid phosphorylation – regulation of the force of heart contraction – response to hydrogen peroxide – response to organic cyclic substance – response to oxidative stress – tachykinin receptor signaling pathway – phosphorylation – intracellular protein transport – muscarinic acetylcholine receptor signaling pathway – regulation of signal transduction – proteolysis

Adrenergic, Beta, Receptor Kinase 1 ist wie folgt lokalisiert:

integral to plasma membrane – membrane fraction – plasma membrane – integral to membrane – microsome – axon – caveola – cytoplasm – cytosol – dendritic shaft – dendritic spine – membrane – synapse

Quelle: NCBI Entrez Gene, Gene Ontology