Die folgenden Gennamen und Gensymbole werden für Antigen Adenosine A2 Receptor über verschiedene Spezies hinweg verwendet:

adenosine A2a receptor (ADORA2A)

Zu den weiteren Synonymen zählen:

RDC8, hA2aR, ADORA2

Auf Proteinebene tauchen folgende Bezeichner für Antigen Adenosine A2 Receptor auf:

adenosine receptor A2a – OTTHUMP00000198454 – OTTHUMP00000198455 – adenosine A2 receptor – adenosine receptor subtype A2a

Adenosine A2 Receptor erfüllt eine Reihe von Funktionen:

G-protein coupled receptor activity – adenosine receptor activity, G-protein coupled – enzyme binding – nonmuscle alpha-actinin binding – protein binding – protein heterodimerization activity – receptor activity – type 5 metabotropic glutamate receptor binding

Adenosine A2 Receptor spielt in den folgenden Prozessen eine Rolle:

G-protein signaling, coupled to cAMP nucleotide second messenger – activation of adenylate cyclase activity – activation of adenylate cyclase activity by G-protein signaling pathway – activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway – adenosine receptor signaling pathway – apoptosis – astrocyte activation – blood circulation – blood coagulation – cAMP biosynthetic process – cell-cell signaling – cellular defense response – central nervous system development – diuresis – eating behavior – induction of apoptosis in response to chemical stimulus – inflammatory response – locomotory behavior – natriuresis – negative regulation of alpha-beta T cell activation – negative regulation of caspase activity – negative regulation of cell proliferation – negative regulation of inflammatory response – negative regulation of locomotion – negative regulation of neuron apoptosis – negative regulation of protein kinase activity – negative regulation of vascular permeability – neuron projection morphogenesis – phagocytosis – positive regulation of acetylcholine secretion – positive regulation of cAMP biosynthetic process – positive regulation of glutamate secretion – positive regulation of protein secretion – positive regulation of synaptic transmission, GABAergic – positive regulation of synaptic transmission, glutamatergic – prepulse inhibition – regulation of calcium ion transport via voltage-gated calcium channel activity – regulation of excitatory postsynaptic membrane potential – regulation of inhibitory postsynaptic membrane potential – regulation of mitochondrial membrane potential – regulation of norepinephrine secretion – regulation of synaptic plasticity – regulation of transcription, DNA-dependent – response to amphetamine – response to caffeine – sensory perception – synaptic transmission, cholinergic – synaptic transmission, dopaminergic – transmembrane receptor protein tyrosine kinase signaling pathway – vasodilation

Adenosine A2 Receptor ist wie folgt lokalisiert:

asymmetric synapse – axolemma – axon – dendrite – endomembrane system – integral to plasma membrane – intermediate filament – intracellular organelle part – membrane fraction – neuronal cell body – plasma membrane – postsynaptic density – postsynaptic membrane – presynaptic active zone – presynaptic membrane

Quelle: NCBI Entrez Gene, Gene Ontology