Die folgenden Gennamen und Gensymbole werden für Antigen Adenosine A1 Receptor über verschiedene Spezies hinweg verwendet:

adenosine A1 receptor (ADORA1), adenosine A1 receptor (Adora1), adenosine A1 receptor (adora1-A), A1 adenosine receptor (LOC606743), adenosine A1 receptor (adora1), adenosine A1 receptor (LOC100222054), A1 adenosine receptor (LOC100328615)

Zu den weiteren Synonymen zählen:

RDC7, Ri, A1R, A1AR, AA1R, A1-AR, AI848715, BB176431, ADORA1, adora1-A, a1R, LOC606743, Adora1, DKFZp469D1021, LOC100222054, LOC100328615

Auf Proteinebene tauchen folgende Bezeichner für Antigen Adenosine A1 Receptor auf:

adenosine A1 receptor – OTTHUMP00000039091 – A1 adenosine receptor – Adenosine receptor A1

Adenosine A1 Receptor erfüllt eine Reihe von Funktionen:

G-protein coupled receptor activity – adenosine receptor activity, G-protein coupled – receptor activity – signal transducer activity – G-protein beta/gamma-subunit binding – heterotrimeric G-protein binding – protein heterodimerization activity – purine nucleoside binding

Adenosine A1 Receptor spielt in den folgenden Prozessen eine Rolle:

G-protein coupled receptor protein signaling pathway – cell-cell signaling – induction of apoptosis by extracellular signals – inflammatory response – nervous system development – phagocytosis – signal transduction – negative regulation of inflammatory response – negative regulation of leukocyte migration – negative regulation of mucus secretion – regulation of excitatory postsynaptic membrane potential – activation of MAPKK activity – inhibition of adenylate cyclase activity by G-protein signaling – natriuresis – negative regulation of apoptosis – negative regulation of cell proliferation – negative regulation of circadian sleep/wake cycle, sleep – negative regulation of glutamate secretion – negative regulation of heart contraction – negative regulation of hormone secretion – negative regulation of lipid catabolic process – negative regulation of synaptic transmission, GABAergic – negative regulation of synaptic transmission, glutamatergic – negative regulation of vasodilation – positive regulation of blood pressure – positive regulation of nucleoside transport – positive regulation of peptide secretion – positive regulation of potassium ion transport – positive regulation of protein amino acid dephosphorylation – regulation of respiratory gaseous exchange by neurological system process – regulation of synaptic plasticity – regulation of vasodilation – temperature homeostasis

Adenosine A1 Receptor ist wie folgt lokalisiert:

integral to plasma membrane – plasma membrane – integral to membrane – membrane – asymmetric synapse – axolemma – basolateral plasma membrane – cell soma – dendrite – endomembrane system – endoplasmic reticulum – postsynaptic density – postsynaptic membrane – presynaptic active zone – presynaptic membrane – terminal button

Quelle: NCBI Entrez Gene, Gene Ontology