Die folgenden Gennamen und Gensymbole werden für Antigen Activin A Receptor, Type IIB über verschiedene Spezies hinweg verwendet:

activin A receptor, type I (ACVR1), activin A receptor, type IIB (ACVR2B), activin receptor IIB (Acvr2b), activin A receptor, type IIB (Acvr2b), activin receptor IIb (acvr2b), activin type IIB receptor (Acvr2b), activin A receptor, type IIB (acvr2b)

Zu den weiteren Synonymen zählen:

FOP, ALK2, SKR1, TSRI, ACTRI, ACVR1A, ACVRLK2, ACTRIIB, ActR-IIB, MGC116908, ActRIIB, MGC118477, actr2b, actrIIb, wu:fj97d11, ACVR2B, Acvr2b, actriib, MGC89569, actr-iib

Auf Proteinebene tauchen folgende Bezeichner für Antigen Activin A Receptor, Type IIB auf:

activin A receptor, type I – OTTHUMP00000204604 – OTTHUMP00000204626 – hydroxyalkyl-protein kinase – TGF-B superfamily receptor type I – activin A receptor, type II-like kinase 2 – serine/threonine-protein kinase receptor R1 – activin A receptor, type IIB – activin receptor IIB – ActRIIB type II activin receptor B – Activine receptor 2b (transmembrane serine kinase) – activin receptor – activin receptor type IIB – testicular activin receptor IIB – activin receptor type-2B-like – activin type IIB receptor

Activin A Receptor, Type IIB erfüllt eine Reihe von Funktionen:

ATP binding – SMAD binding – activin binding – activin receptor activity, type I – follistatin binding – magnesium ion binding – manganese ion binding – nucleotide binding – protein homodimerization activity – receptor activity – transferase activity – transforming growth factor beta binding – activin receptor activity, type II – growth factor binding – activin receptor activity – kinase activity – metal ion binding – protein binding – protein kinase activity – protein serine/threonine kinase activity – protein serine/threonine/tyrosine kinase activity – receptor signaling protein serine/threonine kinase activity – transforming growth factor beta receptor activity – transmembrane receptor protein serine/threonine kinase activity – inhibin beta-A binding – inhibin beta-B binding

Activin A Receptor, Type IIB spielt in den folgenden Prozessen eine Rolle:

BMP signaling pathway – G1/S transition of mitotic cell cycle – acute inflammatory response – determination of left/right symmetry – embryonic development – gastrulation with mouth forming second – germ cell development – heart development – in utero embryonic development – mesoderm development – mesoderm formation – negative regulation of activin receptor signaling pathway – negative regulation of apoptosis – neural crest cell migration – patterning of blood vessels – pharyngeal system development – positive regulation of bone mineralization – positive regulation of osteoblast differentiation – positive regulation of transcription – protein amino acid phosphorylation – regulation of ossification – regulation of skeletal muscle tissue development – smooth muscle cell differentiation – transforming growth factor beta receptor signaling pathway – urogenital system development – anterior/posterior pattern formation – positive regulation of activin receptor signaling pathway – regulation of transcription – signal transduction – activation of protein kinase activity – activin receptor signaling pathway – embryonic foregut morphogenesis – insulin secretion – kidney development – lung development – odontogenesis of dentine-containing tooth – organ growth – palate development – pancreas development – pattern specification process – post-embryonic development – response to glucose stimulus – skeletal system development – skeletal system morphogenesis – transmembrane receptor protein serine/threonine kinase signaling pathway – sexual reproduction – cartilage development – hindbrain development

Activin A Receptor, Type IIB ist wie folgt lokalisiert:

activin receptor complex – apical part of cell – membrane – cell surface – cytoplasm – integral to plasma membrane – plasma membrane – integral to membrane

Quelle: NCBI Entrez Gene, Gene Ontology