Die folgenden Gennamen und Gensymbole werden für Antigen Acetylcholinesterase über verschiedene Spezies hinweg verwendet:

acetylcholinesterase (Yt blood group) (ACHE), acetylcholinesterase (Ache), Acetylcholine esterase (Ace), acetylcholinesterase (ache), acetylcholinesterase (ACHE), Acetylcholine esterase (Dsim\Ace)

Zu den weiteren Synonymen zählen:

YT, ARACHE, N-ACHE, mE1a, mE1b, mE1c, mE1d, mE1e, mE1d', mE1c-long, ACE, AChE, AcChE, CHE, DmAChE, FBgn0000024, dAChE, l(3)26, l(3)87Ed, DmelCG17907, CG17907, zgc:92550, ACHE, Ache, GB14873, dsim_GLEANR_4292, Dsim\GD20515, GD20515, arache, n-ache, ache

Auf Proteinebene tauchen folgende Bezeichner für Antigen Acetylcholinesterase auf:

acetylcholinesterase – OTTHUMP00000211347 – OTTHUMP00000211349 – OTTHUMP00000211356 – apoptosis-related acetylcholinesterase – OTTMUSP00000024159 – OTTMUSP00000024163 – acetylcholine esterase – CG17907-PA – Ace-PA – glycolipid-anchored form of acetylcholinesterase – zim – ziehharmonika – Dsim\Ace-PA – Dsim\GD20515-PA – GD20515-PA – acetylcholinesterase (Yt blood group)

Acetylcholinesterase erfüllt eine Reihe von Funktionen:

acetylcholine binding – acetylcholinesterase activity – beta-amyloid binding – cholinesterase activity – collagen binding – laminin-1 binding – protein homodimerization activity – serine hydrolase activity – carboxylesterase activity – choline binding – hydrolase activity – identical protein binding – laminin binding – protein self-association

Acetylcholinesterase spielt in den folgenden Prozessen eine Rolle:

DNA replication – acetylcholine catabolic process in synaptic cleft – amyloid precursor protein metabolic process – cell adhesion – cell proliferation – muscle organ development – negative regulation of synaptic transmission, cholinergic – osteoblast development – positive regulation of protein secretion – response to wounding – synapse assembly – acetylcholine catabolic process – acetylcholine metabolic process – choline metabolic process – neurotransmitter catabolic process – neurotransmitter receptor biosynthetic process – positive regulation of axonogenesis – positive regulation of dendrite morphogenesis – protein tetramerization – receptor internalization – regulation of receptor recycling – retina development in camera-type eye – choline catabolic process – phototaxis – response to carbamate – response to organophosphorus – synaptic transmission – myofibril assembly – neuromuscular junction development – neuron development – regulation of synapse structure and activity – response to amphetamine – response to chemical stimulus – response to ethanol

Acetylcholinesterase ist wie folgt lokalisiert:

Golgi apparatus – anchored to membrane – basal lamina – cell junction – external side of plasma membrane – extracellular region – extrinsic to membrane – nucleus – perinuclear region of cytoplasm – plasma membrane – synapse – axon – cell surface – cytoplasm – dendrite – endoplasmic reticulum lumen – extracellular space – membrane – neuron projection – neuronal cell body – nuclear envelope – postsynaptic membrane – presynaptic membrane – rough endoplasmic reticulum – cell soma

Quelle: NCBI Entrez Gene, Gene Ontology