Die folgenden Gennamen und Gensymbole werden für Antigen Abl-Interactor 1 über verschiedene Spezies hinweg verwendet:

abl-interactor 1 (ABI1), abl-interactor 1 (Abi1), abl-interactor 1a (abi1a), abl-interactor 1 (abi1), abl-interactor 2 (abi2), abl-interactor 1b (abi1b), Abl-interactor 1 (Bm1_44660), Abl interactor 1 (abi1), abl-interactor 1 (LOAG_04356)

Zu den weiteren Synonymen zählen:

E3B1, ABI-1, NAP1BP, SSH3BP, SSH3BP1, NAP1, MGC6064, Ssh3bp1, E3b1, abi1, MGC73174, zgc:73174, wu:fc66g09, wu:fk56a10, ABI1, MGC84356, e3b1, abi-1, nap1bp, ssh3bp, ssh3bp1, MGC79488, MGC139877, abi-2, abi2b, aip-1, ablbp3, argbpia, argbpib, ssh3bp2, MGC153534, wu:fe48a10, zgc:153534, DKFZp469P1319

Auf Proteinebene tauchen folgende Bezeichner für Antigen Abl-Interactor 1 auf:

abl-interactor 1 – Abelson interactor 1 – eps8 binding protein – nap1 binding protein – interactor protein AblBP4 – Abl-interactor protein 1 long – spectrin SH3 domain binding protein 1 – abl interactor 1 – abi-1 – ablphilin-1 – OTTMUSP00000044749 – OTTMUSP00000044765 – OTTMUSP00000044767 – OTTMUSP00000044768 – OTTMUSP00000044769 – OTTMUSP00000044770 – abelson interactor 1 – eps8-binding protein – eps8 SH3 domain-binding protein – spectrin SH3 domain-binding protein 1 – eps8 binding protein (e3B1), alternatively spliced – abl-interactor 1a – abl-interactor 2 – abl interactor 2 – Abl-interactor 1 – Abl interactor 1 – abl interactor 1-like

Abl-Interactor 1 erfüllt eine Reihe von Funktionen:

cytoskeletal protein binding – protein binding – protein tyrosine kinase activator activity – cell junction – cytoplasm – cytoskeleton – filopodium – growth cone – lamellipodium – nucleus – synapse – synaptosome – molecular_function

Abl-Interactor 1 spielt in den folgenden Prozessen eine Rolle:

negative regulation of cell proliferation – peptidyl-tyrosine phosphorylation – transmembrane receptor protein tyrosine kinase signaling pathway – cellular process – positive regulation of phosphorylation – positive regulation of protein tyrosine kinase activity – somitogenesis – biological_process

Abl-Interactor 1 ist wie folgt lokalisiert:

cell junction – cytoplasm – cytoskeleton – cytosol – endoplasmic reticulum – filopodium – growth cone – intracellular – lamellipodium – nucleus – soluble fraction – synapse – synaptosome – cell leading edge – cell projection

Quelle: NCBI Entrez Gene, Gene Ontology