Die folgenden Gennamen und Gensymbole werden für Antigen Abelson Murine Leukemia Viral Oncogene Homolog 1/2 über verschiedene Spezies hinweg verwendet:

c-abl oncogene 1, receptor tyrosine kinase (ABL1), c-abl oncogene 1, non-receptor tyrosine kinase (Abl1), v-abl Abelson murine leukemia viral oncogene homolog 1 (ABL1), v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) (ABL2), v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) (Abl2), v-abl Abelson murine leukemia viral oncogene homolog 2 (abl2), v-abl Abelson murine leukemia viral oncogene homolog 2 (ABL2)

Zu den weiteren Synonymen zählen:

ABL, JTK7, p150, c-ABL, v-abl, bcr/abl, Abl, c-Abl, AI325092, MGC117749, E430008G22Rik, ABL1, ARG, ABLL, FLJ22224, FLJ31718, FLJ41441, Arg, Abll, AA536808, MGC169395, ABL2, CABL, cb272

Auf Proteinebene tauchen folgende Bezeichner für Antigen Abelson Murine Leukemia Viral Oncogene Homolog 1/2 auf:

c-abl oncogene 1, receptor tyrosine kinase – bcr/c-abl oncogene protein – proto-oncogene tyrosine-protein kinase ABL1 – v-abl Abelson murine leukemia viral oncogene homolog 1 – tyrosine-protein kinase ABL1 – p150 – OTTMUSP00000013005 – proto-oncogene c-Abl – Abelson murine leukemia oncogene – v-abl Abelson murine leukemia oncogene 1 – abelson murine leukemia viral oncogene homolog 1 – Abelson murine leukemia viral (v-abl) oncogene homolog 1 – arg tyrosine kinase – Abelson-related – OTTHUMP00000033140 – Abelson murine leukemia viral (v-abl) oncogene homolog 2 – tyrosine-protein kinase ABL2 – tyrosine kinase ARG – tyrosine-protein kinase ARG – Abelson-related gene protein – abelson murine leukemia viral oncogene homolog 2 – Abl1-related gene product – v-abl Abelson murine leukemia viral oncogene 2 – v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) – tyrosine kinase ABL – arg, Abelson-related – v-abl Abelson murine leukemia viral oncogene homolog 2 – tyrosine-protein kinase ABL2-like

Abelson Murine Leukemia Viral Oncogene Homolog 1/2 erfüllt eine Reihe von Funktionen:

ATP binding – DNA binding – magnesium ion binding – manganese ion binding – non-membrane spanning protein tyrosine kinase activity – nucleotide binding – protein C-terminus binding – transferase activity – kinase activity – metal ion binding – protein binding – protein domain specific binding – protein kinase activity – protein tyrosine kinase activity – molecular_function

Abelson Murine Leukemia Viral Oncogene Homolog 1/2 spielt in den folgenden Prozessen eine Rolle:

DNA damage response, signal transduction resulting in induction of apoptosis – actin cytoskeleton organization – cell adhesion – mismatch repair – peptidyl-tyrosine phosphorylation – positive regulation of oxidoreductase activity – protein modification process – regulation of transcription during S-phase of mitotic cell cycle – regulation of transcription, DNA-dependent – positive regulation of apoptosis – protein amino acid phosphorylation – regulation of cell cycle – signal transduction – actin filament bundle assembly – actin filament organization – actin filament bundle formation – biological_process

Abelson Murine Leukemia Viral Oncogene Homolog 1/2 ist wie folgt lokalisiert:

cytoplasm – cytoskeleton – nucleolus – nucleus – cytosol – plasma membrane – actin cytoskeleton – cytoplasmic membrane-bounded vesicle – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology