Die folgenden Gennamen und Gensymbole werden für Antigen ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 über verschiedene Spezies hinweg verwendet:

ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (ABCC8), ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8)

Zu den weiteren Synonymen zählen:

HI, SUR, HHF1, MRP8, PHHI, SUR1, ABC36, HRINS, TNDM2, Sur, Sur1

Auf Proteinebene tauchen folgende Bezeichner für Antigen ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 auf:

ATP-binding cassette, sub-family C, member 8 – sulfonylurea receptor (hyperinsulinemia) – ATP-binding cassette sub-family C member 8 – sulfonylurea receptor 1 – ATP-binding cassette subfamily C (CFTR/MRP) member 8 – ATP-binding cassette transporter sub-family C member 8 – ATP-binding cassette, subfamily C (CFTR/MRP), member 8 – ATP-binding cassette, sub-family C (CFTR/MRP), member 8 – ATP-binding cassette transporter sub-family C member 8-like

ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 erfüllt eine Reihe von Funktionen:

ATP binding – ATPase activity – ATPase activity, coupled to transmembrane movement of substances – nucleotide binding – potassium ion transmembrane transporter activity – receptor activity – sulfonylurea receptor activity – potassium channel activity – syntaxin binding

ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 spielt in den folgenden Prozessen eine Rolle:

carbohydrate metabolic process – potassium ion transport – transport – negative regulation of insulin secretion – positive regulation of potassium ion transport – response to chemical stimulus – response to drug – response to insulin stimulus – response to lipopolysaccharide – response to pH – response to zinc ion – transmembrane transport

ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 ist wie folgt lokalisiert:

integral to membrane – plasma membrane – ATP-sensitive potassium channel complex – sarcolemma – synaptic vesicle membrane – membrane

Quelle: NCBI Entrez Gene, Gene Ontology