Die folgenden Gennamen und Gensymbole werden für Antigen ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 3 über verschiedene Spezies hinweg verwendet:

transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (TAP2), transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (Tap2), ATP-binding cassette, sub-family B (MDR/TAP), member 3 (abcb3)

Zu den weiteren Synonymen zählen:

APT2, PSF2, ABC18, ABCB3, RING11, D6S217E, Y1, jas, Ham2, MTP2, Abcb3, Ham-2, Tap-2, AI462429, TAP, tap2, si:dz179b20.3, abcb3

Auf Proteinebene tauchen folgende Bezeichner für Antigen ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 3 auf:

transporter 2, ATP-binding cassette, sub-family B – ABC transporter, MHC 2 – peptide supply factor 2 – peptide transporter PSF2 – antigen peptide transporter 2 – transporter 2, ABC (ATP binding cassette) – ATP-binding cassette, sub-family B (MDR/TAP), member 3 – histocompatibility antigen modifier 2 – ATP dependent transport protein family member – transporter 2, ATP-binding cassette – transporter associated with antigen-processing 2 – Antigen peptide transporter 2

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 3 erfüllt eine Reihe von Funktionen:

ATP binding – ATPase activity – ATPase activity, coupled to transmembrane movement of substances – MHC class I protein binding – homoaconitate hydratase activity – nucleotide binding – peptide antigen binding – peptide antigen-transporting ATPase activity – peptide transporter activity – phosphate binding – protein heterodimerization activity – tapasin binding – transporter activity – nucleoside-triphosphatase activity – protein binding – copper ion binding

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 3 spielt in den folgenden Prozessen eine Rolle:

antigen processing and presentation of endogenous peptide antigen via MHC class I – cytosol to ER transport – immune response – interspecies interaction between organisms – intracellular protein transport – peptide transport – protein complex assembly – antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent – positive regulation of T cell mediated cytotoxicity – protein transport – response to molecule of bacterial origin – transport – oxidation reduction – response to methylmercury

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 3 ist wie folgt lokalisiert:

TAP complex – cytosol – endoplasmic reticulum – endoplasmic reticulum lumen – integral to membrane – membrane – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology