Die folgenden Gennamen und Gensymbole werden für Antigen ADP-Ribosylation Factor 6 über verschiedene Spezies hinweg verwendet:

ADP-ribosylation factor 6 (arf6.2), ADP-ribosylation factor 6 (arf6), adenosine deaminase (ADA), ADP-ribosylation factor 1 (ARF1), ADP-ribosylation factor 3 (ARF3), ADP-ribosylation factor 5 (ARF5), ADP-ribosylation factor 6 (ARF6), ADP-ribosylation factor 1 (Arf1), ADP-ribosylation factor 6 (Arf6), ADP-ribosylation factor GTPase activating protein 3 (ARFGAP3), ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1), ADP-ribosylation factor GTPase activating protein 3 (Arfgap3), ADP-ribosylation factor 1 (arf1), ADP-ribosylation factor GTPase activating protein 1 (Arfgap1), ADP-ribosylation factor 1 (arf-1), ADP-ribosylation factor GTPase activating protein 1 (arfgap1), ATARF1 (ADP-RIBOSYLATION FACTOR 1); GTP binding / phospholipase activator/ protein binding (ATARF1), ADP-ribosylation factor GTPase activating protein 1 (Tc00.1047053507507.20), ADP-ribosylation factor GTPase activating protein 1 (Tc00.1047053506871.30), ADP-ribosylation factor GTPase activating protein 1 (Tb11.01.6060), ADP-ribosylation factor 1 (NCU08340), ADP-ribosylation factor GTPase activating protein 1 (LmjF32.1230), ADP-ribosylation factor 1 (TRIADDRAFT_63238), ADP-ribosylation factor 1 (PAAG_08805), ATP-dependent RNA helicase DBP9 (MGYG_02419)

Zu den weiteren Synonymen zählen:

MGC80156, arf6, MGC79593, DKFZp564M0264, AI788669, AW496366, MGC102530, ARFGAP1, FLJ45618, ARF1GAP, MGC39924, HRIHFB2281, MGC72830, Arfgap1, 0610009H19Rik, 1810004P07Rik, 1810035F16Rik, 9130416J18Rik, wu:fb33e02, wu:fb78h01, Arf1gap, AI115377, Arf GAP1, MGC53624, arf2, MGC52628, arf-1, MGC52573, MGC76053, ARF1, arfgap1, MGC83573, ARFGAP3, ADP-RIBOSYLATION FACTOR, ADP-RIBOSYLATION FACTOR 1, ADP-RIBOSYLATION FACTOR 1A, ATARF, ATARF1, ATARFA1A, F28C11.12, lqt, rws, wrs, lqt1, sqt2, atfb1, atfb3, jlns1, kcna8, kcna9, kv1.9, kv7.1, kvlqt1, arf1gap, k(v)7.1

Auf Proteinebene tauchen folgende Bezeichner für Antigen ADP-Ribosylation Factor 6 auf:

ADP-ribosylation factor 6 – adenosine deaminase – adenosine aminohydrolase – ADP-ribosylation factor 1 – ADP-ribosylation factor 3 – small GTP binding protein – ADP-ribosylation factor protein 3 – ADP-ribosylation factor 5 – OTTMUSP00000006686 – ADP-ribosylation factor GTPase activating protein 3 – ADP-ribosylation factor GTPase activating protein 1 – GAP protein – ARF1-directed GTPase-activating protein – ADP-ribosylation factor 1 GTPase activating protein – ADP-ribosylation factor GTPase-activating protein 3 – ARF GAP 3 – ARF1 GAP – OTTMUSP00000017646 – ATARF1 (ADP-RIBOSYLATION FACTOR 1); GTP binding / phospholipase activator/ protein binding – ATP-dependent RNA helicase DBP9

ADP-Ribosylation Factor 6 erfüllt eine Reihe von Funktionen:

adenosine deaminase activity – hydrolase activity – protein binding – zinc ion binding – GTP binding – GTPase activity – nucleotide binding – receptor signaling protein activity – ARF GTPase activator activity – metal ion binding – protein transporter activity – GTPase activator activity – molecular_function – phospholipase activator activity – DNA binding

ADP-Ribosylation Factor 6 spielt in den folgenden Prozessen eine Rolle:

Peyer's patch development – adenosine catabolic process – dATP catabolic process – deoxyadenosine catabolic process – embryonic gut development – germinal center B cell differentiation – hypoxanthine biosynthetic process – in utero embryonic development – inosine biosynthetic process – liver development – lung alveolus development – negative regulation of adenosine receptor signaling pathway – negative regulation of apoptosis – negative regulation of inflammatory response – negative regulation of leukocyte migration – negative regulation of mature B cell apoptosis – negative regulation of mucus secretion – negative regulation of penile erection – negative regulation of thymocyte apoptosis – nucleotide metabolic process – placenta development – positive regulation of B cell proliferation – positive regulation of T cell differentiation in the thymus – positive regulation of T cell receptor signaling pathway – positive regulation of alpha-beta T cell differentiation – positive regulation of calcium-mediated signaling – positive regulation of germinal center formation – positive regulation of heart rate – positive regulation of smooth muscle contraction – purine nucleotide salvage – purine ribonucleoside monophosphate biosynthetic process – regulation of cell-cell adhesion mediated by integrin – response to hypoxia – trophectodermal cell differentiation – xanthine biosynthetic process – COPI coating of Golgi vesicle – membrane organization – post-Golgi vesicle-mediated transport – protein transport – retrograde vesicle-mediated transport, Golgi to ER – small GTPase mediated signal transduction – vesicle-mediated transport – apoptosis – cell adhesion – cell motion – cortical actin cytoskeleton organization – negative regulation of receptor-mediated endocytosis – positive regulation of actin filament polymerization – regulation of Rac protein signal transduction – ruffle organization – transport – intracellular protein transport – protein secretion – regulation of ARF GTPase activity – biological_process – actin cytoskeleton organization – dendrite development – semicircular canal development – response to cadmium ion

ADP-Ribosylation Factor 6 ist wie folgt lokalisiert:

cytoplasm – cytosol – external side of plasma membrane – lysosome – membrane – Golgi apparatus – Golgi membrane – intracellular – plasma membrane – sarcomere – cell cortex – endosome – membrane fraction – ruffle – endomembrane system – internal side of plasma membrane – cellular_component – early endosome – recycling endosome – perinuclear region of cytoplasm – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology