Die folgenden Gennamen und Gensymbole werden für Antigen ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 2 über verschiedene Spezies hinweg verwendet:

ADAM metallopeptidase with thrombospondin type 1 motif, 2 (ADAMTS2), ADAM metallopeptidase with thrombospondin type 1 motif, 8 (ADAMTS8), ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5), ADAM metallopeptidase with thrombospondin type 1 motif, 7 (ADAMTS7), a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7 (Adamts7), ADAM metallopeptidase with thrombospondin type 1 motif, 5 (Adamts5), ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2) (ADAMTS5)

Zu den weiteren Synonymen zählen:

NPI, PCINP, PCPNI, hPCPNI, ADAM-TS2, ADAMTS-3, METH2, ADAM-TS8, FLJ41712, ADMP-2, ADAMTS11, FLJ36738, ADAM-TS7, DKFZp434H204, ADAMTS7B, ADAMTS5, ADAMTS-11

Auf Proteinebene tauchen folgende Bezeichner für Antigen ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 2 auf:

ADAM metallopeptidase with thrombospondin type 1 motif, 2 – procollagen I N-proteinase – procollagen N-endopeptidase – a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2 – ADAM metallopeptidase with thrombospondin type 1 motif, 8 – a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8 – ADAM metallopeptidase with thrombospondin type 1 motif, 5 – aggrecanase-2 – a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) – ADAM metallopeptidase with thrombospondin type 1 motif, 7 – COMPase – a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein – a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7 – metalloprotease – ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2) – a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)

ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 2 erfüllt eine Reihe von Funktionen:

metal ion binding – metalloendopeptidase activity – peptidase activity – zinc ion binding – heparin binding – integrin binding – low affinity phosphate transmembrane transporter activity – hydrolase activity – metallopeptidase activity

ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 2 spielt in den folgenden Prozessen eine Rolle:

collagen catabolic process – proteolysis – negative regulation of cell proliferation

ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 2 ist wie folgt lokalisiert:

extracellular region – proteinaceous extracellular matrix – cell surface – extracellular matrix

Quelle: NCBI Entrez Gene, Gene Ontology