Die folgenden Gennamen und Gensymbole werden für Antigen Activin A Receptor Type II-Like 1 über verschiedene Spezies hinweg verwendet:

activin A receptor, type I (ACVR1), activin A receptor type II-like 1 (ACVRL1), activin A receptor type II-like 1 (Acvrl1), activin A receptor type II-like 1 (acvrl1)

Zu den weiteren Synonymen zählen:

FOP, ALK2, SKR1, TSRI, ACTRI, ACVR1A, ACVRLK2, HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, TSR-I, ACVRLK1, R3, R-3, SETHKIR, MGC91691, ACVRL1, MGC139457, DKFZp459C148, vgb, alk1, zehn1109, hm:zehn1109

Auf Proteinebene tauchen folgende Bezeichner für Antigen Activin A Receptor Type II-Like 1 auf:

activin A receptor, type I – OTTHUMP00000204604 – OTTHUMP00000204626 – hydroxyalkyl-protein kinase – TGF-B superfamily receptor type I – activin A receptor, type II-like kinase 2 – serine/threonine-protein kinase receptor R1 – activin A receptor type II-like 1 – activin A receptor, type II-like kinase 1 – serine/threonine-protein kinase receptor R3 – Activin receptor like kinase 1 – Serine/threonine-protein kinase receptor R3 – serine/threonine-protein kinase receptor R3-like – vbg – violet beauregarde – activin receptor-like kinase 1

Activin A Receptor Type II-Like 1 erfüllt eine Reihe von Funktionen:

ATP binding – SMAD binding – activin binding – activin receptor activity, type I – follistatin binding – magnesium ion binding – manganese ion binding – nucleotide binding – protein homodimerization activity – receptor activity – transferase activity – transforming growth factor beta binding – protein binding – receptor signaling protein serine/threonine kinase activity – transforming growth factor beta receptor activity, type I – transmembrane receptor protein serine/threonine kinase activity – kinase activity – protein kinase activity – protein serine/threonine kinase activity

Activin A Receptor Type II-Like 1 spielt in den folgenden Prozessen eine Rolle:

BMP signaling pathway – G1/S transition of mitotic cell cycle – acute inflammatory response – determination of left/right symmetry – embryonic development – gastrulation with mouth forming second – germ cell development – heart development – in utero embryonic development – mesoderm development – mesoderm formation – negative regulation of activin receptor signaling pathway – negative regulation of apoptosis – neural crest cell migration – patterning of blood vessels – pharyngeal system development – positive regulation of bone mineralization – positive regulation of osteoblast differentiation – positive regulation of transcription – protein amino acid phosphorylation – regulation of ossification – regulation of skeletal muscle tissue development – smooth muscle cell differentiation – transforming growth factor beta receptor signaling pathway – urogenital system development – angiogenesis – negative regulation of cell adhesion – negative regulation of cell growth – negative regulation of cell proliferation – negative regulation of endothelial cell migration – negative regulation of focal adhesion formation – positive regulation of BMP signaling pathway – regulation of blood pressure – signal transduction – wound healing, spreading of epidermal cells – blood vessel morphogenesis – protein heterooligomerization – blood vessel development – determination of ventral identity

Activin A Receptor Type II-Like 1 ist wie folgt lokalisiert:

activin receptor complex – apical part of cell – membrane – cell surface – cytoplasm – integral to plasma membrane – plasma membrane – cell soma – dendrite – integral to membrane

Quelle: NCBI Entrez Gene, Gene Ontology