Die folgenden Gennamen und Gensymbole werden für Antigen A Disintegrin and Metalloproteinase with Thrombospondin Motifs 1 über verschiedene Spezies hinweg verwendet:

ADAM metallopeptidase with thrombospondin type 1 motif, 1 (ADAMTS1), a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 (Adamts1), a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) (Adamts5), ADAM metallopeptidase with thrombospondin type 1 motif, 1 (adamts1), ADAM metallopeptidase with thrombospondin type 1 motif, 1 (Adamts1)

Zu den weiteren Synonymen zählen:

C3-C5, METH1, KIAA1346, ADAMTS, METH-1, ADAM-TS1, ADAMTS-1, ASMP-2, ADAMTS1, ADAM-TS5, ADAMTS11, AI481094, 9530092O11Rik, c3-c5, meth1, xadamts1

Auf Proteinebene tauchen folgende Bezeichner für Antigen A Disintegrin and Metalloproteinase with Thrombospondin Motifs 1 auf:

ADAM metallopeptidase with thrombospondin type 1 motif, 1 – human metalloproteinase with thrombospondin type 1 motifs – a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1 – OTTMUSP00000021492 – a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) – implantin – a disintegrin and metalloproteinase with thrombospondin motifs 1 – a disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS-1) – a disintegrin-like and metallopeptidse (reprolysin type) with thrombospondin type 1 motif, 1 – a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1

A Disintegrin and Metalloproteinase with Thrombospondin Motifs 1 erfüllt eine Reihe von Funktionen:

heparin binding – metal ion binding – metalloendopeptidase activity – peptidase activity – protein binding – zinc ion binding – hydrolase activity – metallopeptidase activity

A Disintegrin and Metalloproteinase with Thrombospondin Motifs 1 spielt in den folgenden Prozessen eine Rolle:

heart trabecula formation – integrin-mediated signaling pathway – kidney development – negative regulation of cell proliferation – ovulation from ovarian follicle – proteolysis – negative regulation of angiogenesis

A Disintegrin and Metalloproteinase with Thrombospondin Motifs 1 ist wie folgt lokalisiert:

basement membrane – cytoplasmic vesicle – extracellular region – extracellular matrix – proteinaceous extracellular matrix

Quelle: NCBI Entrez Gene, Gene Ontology