Die folgenden Gennamen und Gensymbole werden für Antigen 5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase über verschiedene Spezies hinweg verwendet:

5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), target of myb1 (chicken)-like 1 (TOM1L1), 5-methyltetrahydrofolate-homocysteine methyltransferase (Mtr), 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (Mtrr), 5-methyltetrahydrofolate-homocysteine methyltransferase (mtr), 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (mtrr), 5-methyltetrahydrofolate--homocysteine methyltransferase (metH), 5-methyltetrahydrofolate-homocysteine methyltransferase (TTC0253), 5-methyltetrahydrofolate--homocysteine methyltransferase (BAS4156), 5-methyltetrahydrofolate--homocysteine methyltransferase (Suden_2031), 5-methyltetrahydrofolate--homocysteine methyltransferase (GbCGDNIH1_0151), 5-methyltetrahydrofolate--homocysteine methyltransferase (Bcer98_2983)

Zu den weiteren Synonymen zählen:

MS, cblG, FLJ33168, FLJ43216, FLJ45386, MSR, cblE, MGC129643, SRCASM, OK/KNS-CL.3, methioninesynthase, 4732420G08, AI894170, D830038K18Rik, MTR, MGC112912, cb830, MTRR, DKFZp469P1116, DKFZp459J1330

Auf Proteinebene tauchen folgende Bezeichner für Antigen 5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase auf:

5-methyltetrahydrofolate-homocysteine methyltransferase – methionine synthase – cobalamin-dependent methionine synthase – vitamin-B12 dependent methionine synthase – 5-methyltetrahydrofolate-homocysteine methyltransferase 1 – methionine synthase reductase – [methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing) – target of myb1-like 1 – target of myb 1-like 1 – Src activating and signaling molecule – 5-methyltetrahydrofolate-homocysteine methyltransferase reductase – Methionine synthase – 5-methyltetrahydrofolate--homocysteine methyltransferase

5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase erfüllt eine Reihe von Funktionen:

cobalamin binding – cobalt ion binding – dihydropteroate synthase activity – homocysteine S-methyltransferase activity – metal ion binding – methionine synthase activity – methyltransferase activity – protein binding – transferase activity – zinc ion binding – FAD binding – FMN binding – NADP or NADPH binding – [methionine synthase] reductase activity – electron carrier activity – iron ion binding – oxidoreductase activity – SH3 domain binding – ubiquitin binding – amino acid binding – folic acid binding – aquacobalamin reductase activity

5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase spielt in den folgenden Prozessen eine Rolle:

cellular amino acid biosynthetic process – cellular metabolic process – folic acid and derivative biosynthetic process – methionine biosynthetic process – nervous system development – oxidation reduction – intracellular protein transport – ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway – homocysteine metabolic process – protein amino acid methylation – tetrahydrofolate metabolic process – protein stabilization

5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase ist wie folgt lokalisiert:

cytoplasm – cytosol – intracellular – mitochondrion – Golgi apparatus – Golgi stack – endosome – endosome membrane – lysosome – membrane – soluble fraction

Quelle: NCBI Entrez Gene, Gene Ontology